Part I - GENERAL WORKS
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Part II 1-METHYL-4-PHENYL-PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER (Dolantin, demerol, meperidine, isonipecaine, dolantol, dolasol, pethidine, mefedina, lidol)
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Part III: 6-DIMETHYLAMINO-4, 4-DIPHENYL-3-HEPTANONE (Amidon (e), methadon (e), dolophine, "10,820", miadone, "AN-148", butalgin)
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Part IV - OTHER SYNTHETIC SUBSTITUTES FOR MORPHINE
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98 ERRATA TO VOLUME II, NO. 1
Pages: 84 to 99
Creation Date: 1950/01/01
The following bibliography embodies that portion of the periodical and other literature on the subject of synthetic substitutes for morphine for which references were available at the seat of the United Nations. All but two of the articles were written after the discovery of dolantin by Eisleb and Schumann in 1939. During the past decade, a great number of articles appeared in technical journals throughout the world, but the difficulty of collecting the references was enhanced by the fact that the war and postwar dislocation hindered the work of the abstracting and indexing journals. Thus, the coverage of journals outside North America is, of necessity, quite incomplete. Every effort has been made, however, to offer as many articles as possible from journals in other parts of the world.
As regards subject-matter, the bibliography contains articles of chemical, pharmacological, medical and clinical interest. There are also references and many articles on me addiction liability of the new synthetic drugs.
The bibliography has been divided into four parts. Part I includes general works; part II covers the works concerned with dolantin; part III contains the works concerned with amidone; while part IV embraces the remaining group of articles which describe, for the most part, those drugs which are similar in chemical structure either to dolantin or to amidone. Within each part, the authors are listed in alphabetical order; in instances where an author has written several articles, the latter are listed according to the alphabetical order of the journal in which they appear.
In a few cases, the original title of an article could not be obtained, and an English translation in parentheses is offered in its place. In such instances, the language of the original article is also mentioned.
ANSLINGER, H. J., Regulatory problems of the new analgesics under the narcotic law, Annals of the New York Academy of Sciences, 1948, 51, pages 134-136.
ASHER, R., A method of testing analgesics, Lancet,London, 1948, 2, 20, pages 771-773.
BADGER, G. M.; COOK J. W.; DONALD, G. M. S.; GRAHAM, J. D. P.; WALKER, T., Synthetic analgesics, Nature,1948, 162, page 21.
BARLTROP, J. A., The synthesis of analgesic substances, Journal of the Chemical Society, 1946 , pages 958-965.
BATTERMAN, Robert C., The importance of addiction to the newer synthetic analgesics in human therapy, Annals of the New York Academy of Sciences, 1948, 51, pages 123-129.
BERGEL, F.; MORRISSON, A. L., Synthetic anlagesics, Quarterly Review, London, 1948, 2, pages 349-382.
BLISS, C. I.; SEVERINGHAUS, E. L., A collaborative study of methods for assaying analgesic drugs, Federation Proceedings, 1947, 6, pages 310-311.
CANBACK, T.1 (in Swedish) (New medicinals), Svensk Farm. Tideskrift, 1948,
52, pages 438-446.
DAVIES, O. J.; RAVENTOS, J.; WALPOLE, A. L., A method for the evaluation of analgesic activity using rats, British Journal of Pharmacology and Chemotherapy, 1946, 1, pages 255-264.
EDDY, N. B., The search for more effective morphine-like alkaloids, American Journal of the Medical Sciences, 1939, 197, pages 464-479.
The original title of this work could not be located.
EDDY, N. B., Newer narcotics, American Practitioner, 1948, 3, pages 37-42.
EDDY, N. B., Progress in drug therapy of pain, American Professional Pharmacist, 1948, 14, page 252.
ELLIOTT, H. W.; SUTHERLAND, V. C.; BOLDREY, E. B., Respiration of human brain slices and the effects of morphine on oxygen uptake, Federation Proceedings, 1949, 8, pages 288-289.
FOURNEAU, E., Pouvoir, analgésique et constitution chimique, Chimie et Industrie, 1938, 39, pages 1043-1057.
GEIGY, J. R., Swiss patents 235,230-235 , 240 (Synthetic Narcotics).
GREWE, R., Synthetische Arzneimittel mit Morphin-Wirkung (Synthetic drugs with morphine action), Angewandte Chemie, 1947, A59, pages 194-199.
GREWE, R., The problem of morphine synthesis, United Nations document E/CN-.7/154. 6 May 1949, 2 pages.
HEBB, C. O.; KONZETT, H., Difference between morphine and synthetic analgesics in their actions on ganglionic transmission, Nature, 1949, 163, pages 720-721.
HELLIJAS, C. S.; TOVELL, R. M.; HOLT, K. R., Analgesia and anesthesia in obstetrics, Anesthesiology, March 1947, 8, pages 113-126.
HERSHENSON, B. B., Use of the new synthetic analgesics in obstetrics, Annals of the New York Academy of Sciences, 1948, 51, pages 151-160.
HEWER, A. J. H.; KEELE, C. A. ( et al.), A clinical method of assessing analgesics, Lancet, 1949, 1, pages 431-435.
HEWER, C. L. Recent Advances in Anaesthesia and Analgesia, 5th ed., London J. & A. Churchill, 1944.
HOUDE, R. W.; RAJMUSSEN, H.; LaDUE, J. S., Preliminery experiences in the use of some of the newer analgesics in the relief of pain and to cancer, Annals of the New York Academy of Sciences, 1948, 51, pages 161-174.
ISBELL, H., The newer analgesic drugs; their use and abuse, Annals of Internal Medicine, 1948, 29, pages 1003-1013.
ISBELL, H., Methods and results of studying experimental human addiction to the newer synthetic analgesics, Annals of the New York Academy of Sciences, 1948, 51, pages 108-122.
JAMES, H. P.; ELLIOTT, H. W.; PAGE, E. W., Oxygen uptake of human placental tissue as affected by selected substrates and drugs, Proceedings of the Society for Experimental Biology and Medicine, 1948, 67, pages 130-132.
KIRCHHOF, A. C., Further studies on synthetic analgesics, Federation Proceedings, 1948, 7, page 234.
LEHMAN, R. A.; KUPPERMAN, H. S.; PHILLIPS, J., Studies on the relationship between chemical constitution and analgesic activity, Federation Proceedings, 1948, 7, pages 237-238.
LEWIS, J. R., Tolerance in rats to new synthetic analgesic drugs, Federation Proceedings, 1949, 8, pages 315-316.
LEWIS, J. R., Development of tolerance in rats to some new synthetic analgesics, Journal of Pharmacology and Experimental Therapeutics, 1949, 96, pages 31-37.
MORRISON, A. L.; RINDERKNECHT, H., Synthetic analgesics, Festschrift fur Emil Christoph Barell, 1946, pages 253-263.
NELSON, E. E., The Federal Food, Drug, and Cosmetic Act and new analgesic drugs, Annals of the New York Academy of Sciences, 1948, 51, pages 130-133.
OBERST, F. W.; REICHARD, J. D.; LEE, L. E., jr.; CLARK, B. B.; HIMMELSBACH, C. K, Symposium: Can the euphoric, analgetic, and physical dependence effects of drugs be separated? Federation Proceedings, 1943, 2, Introduction (Oberst) pages 187-188; I: with reference to euphoria, (Reichard), pages 188-191; II: with reference to analgesia and clinical experience (Lee), pages 191-195; III: non-opiate analgesics (Clark), pages 195-201; IV: with reference to physical dependence (Himmelsbach), pages 201-203.
PFEIFFER, C. C.; SANTOS-MARTINEZ, J.; SHERROD, T. R., The nature of the prosthetic groups of analgesics and their possible action as blocking agents, Federation Proceedings, 1948, 7, pages 248-249.
PHATAK, N. M.; MALONEY, J.; DAVID, N., Use of hyperglycernic response for estimating addiction potentialities of analgesic compounds, Federation Proceedings, 1948, 7, page 249.
PRESCOTT, F.; RANSOM, S. G. (et al.) Effect of analgesics on respiratory response to carbon dioxide in man, Lancet, London 1949, 1, pages 340-344.
ROBSON, J. M.; NISSSIM, J. A., The new analgesics, Chemical Products, 1949, 12, pages 284-292.
ROVENSTINE, E. A., Use of new synthetic analgesics in surgery, Annals of the New York Academy of Sciences, 1948, 51, pages 145-150.
SCHUELER, F. W.; GROSS, E. G.; HOLLAND, H., Chemical constitution and analgetic action, Journal of the American Pharmaceutical Association, 1949, 38, pages 74-81.
SCOTT, C. C.; KOHLSTAEDT, K. G.; CHEN, K. K., Comparison of pharmacologic properties of some new analgesic substances, Current Researches in Anesthesia and Analgesia, January-February 1947, 26, pages 12-17.
SEEVERS, M. H., Animal experimentation in studying addiction to the newer synthetic analgesics, Annals of the New York Academy of Sciences, 1948, 51, pages 98-107.
SEEVERS, M. H., Pharmacology of the newer synthetic analgesics, Journal of Oral Surgery, 1949, 7, pages 30-38.
SMALL, EDDY, MOSETTIG, HIMMELSBACH, Public Health Service, Supplement No. 138, U. S. Treasury Department, Washington 1938.
THORP, R. H., The assessment of analgesic activity in new synthetic drugs, British Journal of Pharmacology and Chemotherapy, 1946, 1, pages 113-126.
VAN DYKE, H. B., New analgesic drugs, Bulletin of the New York Academy of Medicine, 1949, 25, pages 152-175.
WAYNE, E. J.; Current therapeutics VII-the newer analgesics, The Practitioner, 1948, 161, pages 52-58.
WOLFF, P. O., Dolor y euforia; adelantos farmacológicos (Pain and euphoria; pharmacological advances). Ciencia e Investigación, 1948, 4, pages 186-198.
AJAZZI-MANCINI, M., Ricerche farmacologiche su un nuova analgesico antispasmodico: la mefadina; critica al concetto dei rapporti fra costituzione chimica ed azione farmacologica (Pharmacological research on a new antispasmodic analgesic: demerol; observations on the concept of a relationship between the chemical structure and the pharmacological action), Minerva Chirurgica, August 1946, 1, pages 184-194.
D’ALESSIO, R.,2(in Spanish) (Some reactions of ethyl 1-methyl-4-phenylpiperidine-4-carboxylate hydrochloride or dolantin and methods of determination), La Semana Médica, Buenos Aires, 1943, 1, pages 289-293.
ALTHOFF, H., Klinische Erfahrungen mit Dolantin - Bayer (Clinical experiments conducted with dolantin - Bayer). Therapie der Gegenwart, 1939, 80, page 258.
AMARK, C., Om Dolantin och dolantinnarkomani (On dolantin and addiction to dolantin), Nordisk Medicin, Helsinki, 1942, 13, pages 57-64.
ANDA, T., Die Wirkung des Dolantin in der chirurgischen Schmerzstillung (Action of dolantin as an analgesic), Zentralblatt fur Chirurgie, 3 January 1942, 69, .pages 8-10.
ANDREWS, H. L., Development of tolerance to demerol, Journal of Pharmacology and Experimental Therapeutics, August 1942, 75 pages 338-341.
ANDREWS, H. L., Cortical effects of demerol, Journal of Pharmacology and Experimental Therapeutics, September 1942, 76, pages 89-94.
ANSLINGER, H. J., Addiction to demerol and the Readers’ Digest, Journal of the American Medical Association, 13 July 1946, 131, page 937.
ANSLINGER, H. J.; HIMMELSBACH, C. K.; DEKRUIF, P., Correspondence on addiction properties of demerol, Journal of the American Medical Association, 7 September 1946, 132, pages 43-44.
BARLOW, O. W.; CLIMENKO, D. R.; HOMBURGER, E.; Comparative potentiating effects of certain therapeutic agents on sodium evipal hypnosis, Proceedings of the Society for Experimental Biology and Medicine, January 1942, 49, pages 11-13.
2The original title of this work could not be located.
BARNES, J., Pethidine in labour; results in 500 cases, British Medical Journal, 5 April 1947, 1, pages 437-442.
BATTERMAN, R. C., Treatment of arthritic pain with demerol, new synthetic analgesic, Annals of Internal Medicine, March 1945, 22, pages 382-385.
BATTERMAN, R. C., Clinical effectiveness and safety of new analgesic drug, demerol, Archives of Internal Medicine, March 1943, 71, pages 345-356.
BATTERMAN, R. C., Demerol, new synthetic analgesic; its indications as substitute for morphine, Connecticut State Medical Journal, January 1944, 8, pages 13-17.
BATTERMAN, R. C., Demerol, new synthetic analgesic, The General Practitioner of Australia and New Zealand, 15 May 1944, 15, pages 5-8, originally published in The Medical Bulletin of the New York University, College of Medicine.
BATTERMAN, R. C., The effectiveness in man of demerol, a new analgesic drug, Proceedings of the Federation of American Societies for Experimental Biology, 1942, part 2, page 143.
BATTERMAN, R. C., Demerol - new analgesic drug effective for relief of pain in medical and surgical conditions, Transactions of the American Therapeutic Society, 1942, 42, pages 133-138
BATTERMAN, R. C.; HIMMELSBACH, C. K., Demerol - new synthetic analgesic; review of its present status and comparison with morphine, Journal of the American Medical Association, 22 May 1943, 122, pages 222-226.
BATTERMAN, R. C., MULHOLLAND, J. H., Demerol; substitute for morphine in treatment of post-operative pain. Archives of Surgery, March 1943, pages 404-409.
BEATON, D., Pethidine in labour. Edinburgh Medical Journal, 1948, 55, pages 354-361.
BENEDEK, L.; JUBA, A., Beiträge zur Pathologie des Diencephalous (Contributions to the study of diencephalic pathology), Zentralblatt für die gesamte Neurologie und Psychiatrie, 1943, 104, page 293.
Orvostudomanyi Kozlemenyek, 1943, 4, pages 1-4.
BENTHIN, W., Schmerzlinderung in der Geburt durch Dolantin (The suppression of pain in labour through dolantin), Deutsche medizinische Wochenschrift, July 12, 1940, 66, pages 760-762.
BENTHIN, W., Erleichterung, Abkürzung, und Gefahrenminderung der Geburt alter Erstgeborender (Alleviating, shortening and diminishing danger for older primiparous women), Medizinische Klinik, 1942, 15, pages 342-344.
BENTHIN, W., Erfahrungen mit Varon, einem neuen nicht hormonalen Wehenmittel (Experiences with varon, a new non-hormone-containing analgesic against birth pangs), Münchener medizinische Wochenschrift, 14 January 1944, 91, page 16.
BERGEL, F.; MORRISON, A. L.; RINDERKNECHT, H., Synthetic analgesics. Part II. A new synthesis of pethidine and similar compounds, Journal of the Chemical Society, 1944, pages 265-267.
BERNHEIM, F.; BERNHEIM, M. L. C., Hydrolysis of demerol by liver in vitro, Journal of Pharmacology and Experimental Therapeutics, September 1945, 85, pages 74-77.
BISPING, M., Erfahrungen mit Dolantin in der Geburtshilfe (Observations on the use of dolantin in obstetrics), Zentralblatt für Gynäkologie, 1943, 67, pages 628-631.
BOSCHETTI ORTHMANN, A., Contributo allo studio di un nuovo spasmoditico (Contribution to the study of a new spasmolytic), Il Progresso Medico, Naples, 1 March 1947, 3, pages 142-145.
BRANWOOD, A. W., Clinical trials of pethidine , Edinburgh Medical Journal, March 1943, 50, pages 177-182.
BRINDLEY, C. O., Demerol and cholinesterase, Federation Proceedings, March 1944, 3, page 5.
BROUGHER, J. C., Demerol·in obstetrics, Western Journal of Surgery, Obstetrics, and Gynecology, 1948, 56, page 480.
BROWN, J. M.; VOLPITTO, P. P.; TORPIN, R., Intravenous demerol-scopolamine amnesia during labour, Anesthesiology 1949, 10, pages 15-24.
Von BRUCKE, Stefanie, Ueber Dolantinabusus und einen Fall von Dolantindelir (The abuse of dolantin; a case of delirium), Wiener klinische Wochenschrift, 18 October 1940, 53, pages 854-856.
BRUNNER, H., Dolantin bei Singultus (Dolantin for hiccoughs), Wiener medizinische Wochenschrift, 1940, 90, page 272.
BUSCAINO, V. M.; PERO, C., L'analgesia adrenergica; contributo alla fisiopatologica del dolore (The adrenergic analgesis; contributions to the physiopathology of pain), Rivista di Patologia Nervosa e Mentale, Florence ,1941, pages 58-102 (see particularly pages 197-198.
CABALLERO GORDO, A.; ESTEBAN SAN MATEO, L., La dolantina como analgésico y espasmo litico (Demerol as an analgesic and spasmolytic), Farmacoterapia Actual, August 1946, 3, pages 563-572.
CAPRARO, V., 3 (in Italian) (Comparison of the spasmolytic action of dolantin and of new compounds of analogous action ), Farmaco Sciencia e Tecnica, Parvia 1948, 3, pages 137-144.
CARDUS, J., El acortamiento de la duracion del parto por medio de la dolantina (The shortening of the duration of labour by the use of dolantin), Revista Espanola de Obstetricia y Ginecologia, November 1946, 5, pages. 304-308.
CARDUS, J., Cuarenta casos personales de acortamientode la duracion del parto por medio de la dolantina (Forty cases in which labour was shortened by the use of dolantin) Toko-ginecologia Practica, March 1947, 6, pages 95-101,
CARMICHAEL, E. B.; JOHNSON, W. H.; KAY F. A., Toxicity studies with demerol hydrochloride (isonipecaine) on adult male guinea pigs, Federation Proceedings, 1949, 8, page 190.
CARRATALA, R.; LOYARTE, R. G.; VUCETICH, D., Estudio sobre la dolantina (Study on dolantin), Revista de Psiquiatria y Criminologia, Buenos Aires, May-June 1942, 7, pages 139-158.
CARTER, H. M., Role of demerol in obstetrics, Wisconsin Medical Journal, December 1945, pages 1170-1172.
CHRISTENSEN, E. M.; GROSS, E. F., Efecto analgesico comparativo de la morfina, la meperidina, y el metadin (Comparison between the analgesic effects of morphine, meperidine and methadon), América Clinica; revista inter-americana de selecciones de medicina, cirugia y especialidades, 1948, 13, pages 414-417.
CHRISTENSEN, E. M.; GROSS, E. F., Analgesic effects in human subjects
3The original title of this work could not be located.
of morphine, meperidine and methadon, The Journal of the American Medical Association, 1948, 137, pages 594-599.
CHRISTIE, R. V., Analgesic value of pethidine by mouth, Lancet, 6 March 1943, CCXLIV, 1, pages 294-295.
CHU, W. C.; DRIVER, R. L., Effects of some old and proposed anticonvulsants (including isonipecaihe) on the threshold for electrically induced convulsions, Proceedings of the Society for Experimental Biology and Medicine, 1947, 64, pages 245-248.
CLARK, B. B., The effect of syntropan, demerol, and trasentine on gastric secretion, Federation Proceedings, 1947, 6, page 317.
CLARK, B. B.; ROMANO, J. J., A comparison of the effect on gastric secretion of syntropan, demerol, and trasentine with atropine, Gastroenterology, 1947, 9, pages 454-460.
CLIMENKO, D. R.; BERG, H., Influence of demerol on contractions of ureter, Journal of Urology, February 1949, 43, pages 255-258.
CLIMENKO, D. R., 1-methyl-4-phenyl-piperidine-4-carbonic acid-ethyl ester (D-. 140, demerol): a pharmacologically active substance with atropine-like and morphine-like properties, Proceedings of the American Physiological Society, April 1942, in Federation Proceedings, 10 March 1942, 1, 1, part 2, page 15.
COPEN, S. I., Premedication by co-medication in local anesthesia, American Journal of Orthodontics and Oral Surgery (Oral Surgery Section), April 1947, 33, pages 290-300.
CRIPPS, J. A. R.; HALL, B.; HAULTAIN, W. F. T., Analgesia in labour; a record of 102 cases treated with pethidine, British Medical Journal, 14 October 1944, 2, pages 498-500.
CURIA, L., La dolantina en el parkinsonismo (Dolantin in parkinsonism), La Semana Médica, 9 March 1944, 1, pages 501-502.
CURRY, J. J., Habituation to meperidine hydrochloride (demerol hydrochloride), Journal of the American Medical Association, 25 January 1947, 133, pages 243-244.
CURRY, J. J., Clinical appraisal of demerol, benadryl and pyribenzamine, The Medical Clinics of North America, September 1946, 30, pages 1138-1148.
DAWES, G. S., Synthetic substitutes for quinidine, British Medical Journal, 12 January 1946, 1, pages 43-45, also British Journal of Pharmacology and Chemotherapy, 1946, 1, pages 90-111.
DEMEROL within purview of narcotic laws, Journal of the American Medical Society, 29 July 1944, 125, page 914.
DIETRICH, H., Klinische Erfahrungen mit einem neuen synthetischen Spasmolytikum and Analgetikum (Clinical experiments with a new synthetic spasmolytic and analgesic), Deutsche medizinische Wochenschrift, 16 June 1939, 65 pages 969-970.
DOBOS, S.; SIMONYI, G., (in Hungarian) (Experiences with dolantin in therapy of painful neurologic diseases), Gyogyaszat, 17 May 1941, 81 pages 289-290.
DODDS, E. C.; LAWSON, W.; SIMPSON, S. A.; WILLIAMS, P. C., Testing diphenylethylamine compounds for analgesic action , Journal of Physiology, 1945, 104, pages 47-51.
DOLANTIN-Restrictions in Germany as of 1 July 1941, Announcement, Journal of the American Medical Association, August 29, 1942, 1192, page 1518.
DOLLE, W., Dolantin, etc. in der Gynakologie (Dolantin, etc., in gynecology), Praktische Arzt, 1940, 8, page 113.
DONATELLI, L., La mefedina come farmacodi preparazione alla anestesia (Demerol as a drug-preparing anesthesia), Il Policlinico (Sezione chirurgica), September-October 1945, 52, pages 178-207.
DONATELLI, L.; BUFFONI, F., Potenzamento dell'anestesia locale operato della mefedina (Use of demerol in local anesthesia), Bulletino della Société Italiana di Biologia Sperimentale, 1947, 23, pages 288-289.
DONATELLI, L.; di LOLLO, F., Riassorbimento, concentrazione in circolo ed eliminazione della mefedina, Sperimentale (Experiments on reabsorption; concentration in circuits and elimination of demerol), Lo Sperimental, Archivo di Biologia Normale e Patologica, Florence, 1947, 98, pages 590-602.
DONNELLY, J. F., Analgesia in Obstetrics, American Journal of Medical. Sciences, June 1944, 207, pages 804-811.
DONATIEN, M., Le somnifène et le demerol dans l'analgesie obstetricale, Union medicale du Canada, February 1946, 75, pages 154-158.
DOWNS, J. T., Obstetric use of demerol, Texas Journal of Medicine, 1947-48, 43, pages 486-488.
DRAPER, T., Pethidine (demerol), The Journal of the Christian Medical Association of India, Burma and Ceylon, March 1947, 22, page 52-55.
DUGUID, A: M. E.; HEATHCOTE, R. St. A., Pharmacological action of ethyl methyl-phenylpiperidine-carboxlyate, Quartterly Journal of Pharmacy and Pharmacology London, October-December 1940, 13, pages 318-331.
4Ibid.
EISLEB, O., Neue synthesen-mittel Natriumamids (New syntheses with sodium amide), Berichte der deutschen chemischen Gesellschaft, 1941, 74b, pages 1433-1450.
EISLEB, O., Aufbau neuer krampfl?sender und schmerzstillender Mittel (New spasmolytic and anlagesic agents), Medizin und Chemie Abhandlungen aus den medizinisch-chemischen Forschungsstätten der I. G. Farbenindustrie Aktiengesellschaft, 1942, 4, pages 213-228, also Chemisches Zentral-blatt, 1943, 2, page 2072.
EISLEB, O., Patents, British: No. 501, 135; U. S.: Nos. 2,167,351 and 2,242,575.
EISLEB, O.; SCHAUMANN, O., Dolan-tin, ein neuartiges Spasmolytikum und Analgetikum (chemisches und pharmakologisches) (Dolantin, a new spasmolytic and analgesic (chemical and pharmacological)), Deutsche medizinische Wochenschrift, 16 June 1939, 65, pages 967-968.
ELLIOTT, H. W., Comparative effects of 1:1-diphenyl-1-(dimethylaminoisopropyl)-butanone-2 (10820), demerol and morphine on the respiration of rat cerebral cortex slices, Federation Proceedings, 1947, 6, page 327.
ELLIOTT, H. W.; WARRENS, A. E.; JAMES, H. P., Some effects of 1-methyl-4-phenyl ethyl isonipecotate (demerol) and 6-dimethylamino-4, 4-diphenyl-3-heptanone (amidone) upon metabolism of rat brain tissue in vitro, Journal of Pharmacology and Experimental Therapeutics, October 1947, 91, pages 98-102.
ERBSLOH, J., Uber den Dolantin-Effekt beim Neugeborenen (The effects of dolantin on new-born infants), Zentralblatt für Gynäkologie, 1943, 67, pages 578-580.
ERCOLI, N.; LEWIS, M. N., The time-action curves of morphine, codeine, dilaudid, and demerol by various methods of administration; II: Analgesic activity of acetylsalicylic acid and aminopyrine, Journal of Pharmacology and Experimental Therapeutics, 1945, 84, pages 301-317.
ERLENDSSON, V., 5(in Danish) (Therapeutic applications of dolantin), Ugeskrift for Laeger, Copenhagen, 12 December 1940, 102, pages 1330-1331.
ETCHEVERRY, J. A., Tolerancia a una nueva droga (Tolerance to a new drug), La Semana Médica, 23 October 1941, 48, 43, page 1013.
5The original title of this work could not be located.
FABRE, R., Rapport relatif a l'inscription au tableau "A" de l'ester éthylique de l'acide 1-methyl-4-phenylpiperidine-4-carbonique (dolosal) et ses sels, Bulletin de l'Académie de médecine, July 1945, 129, pages 523-524. de FEO, D. A.; OCCHI, A., Ensayos sobre un nuevo analgésico en el parto (Observations on the use of a new analgesic in obstetrics). Archivos de la Clínica obstétrica y ginecológica, Buenos Aires, May 1942, 1, pages 338-349; also see La Semana Médica, 25 June 1942, pages 1334-1338.
FERRER, M. I.; SOKOLOFF, L., Antidiuretic effect of morphine and demerol in congestive heart failure. American Journal of the Medical Sciences, October 1947, 214, pages 372-384.
FERRER BOIRA, J., Estrangulación herniaria en un lactante; reducción incruenta y dolantina (Hernial strangulation in the infant; the role of dolantin in its reduction without loss of blood), Revista española de pediatría, July-August 1946, 2, pages 566-567.
FITZGERALD, G.; McARDLE, B., Effect of pethidine on pain in neurological cases, Lancet, 6 March 1943, CCXLIV., 1, pages 296-297.
FLATT, W. D., Relief of pain in labour with demerol, Canadian Medical Association Journal, July 1946, 55, pages 43-46.
FLIPSE, M. E.; FLIPSE, M. J., Hyperpyrexia due to demerol, Southern Medical Journal, 1949, 42, pages 395-401.
FONGI, E. G., La dolantina en el tratamiento del hipo (Dolantin in the treatment of hiccough), La Semana Médica, 28 October 1943, 2, pages 989-990.
FUSTER, J., Dolant?smo. Necesidad de su restricción como nueva toxicomanía (Demerol addiction: necessity of its restriction as a habit-forming drug), Medicina española, April 1945, 13, pages 304-308.
GAENSLER, E. A.; McGOWAN, J. M.; HENDERSON, F. F., A comparative study of the action of demerol and opium alkaloids in relation to biliary spasm, Surgery, 1948, 23, pages 211-220.
GALLEN, B.; PRESCOTT, F., Pethidine as obstetric analgesic; report on 150 cases, British Medical Journal, 5 February 1944, 1, pages 176-179.
GARCIA-BIRD, J., Demerol-scopolamine analgesia in obstetrics; report of 50 cases, Boletín de la Asociación médica de Puerto Rico, October 1945, 37, pages 414-417.
GARCIA HUIDOBRO, M., Ensayo de un nuevo analgésico en el raspudo uterino (Experiment with a new analgesic in the uterine curetage), Boletin de la Sociedad Chilena de Obstetrica y Ginecologia, Santiago, Chile, October 1941, 6, pages 371-376.
GARDA, D., El uso clínico de la dolantina y su abuso por los toxicómanos (The clinical use of dolantin and its abuse by drug addicts), Día Médico, Buenos Aires, 1941, 13, page 1053.
GAUTHIER, P., Analgésie en obstétrique. Union médicale du Canada, February 1946, 75, pages 158-160.
GILBERT, G.; DIXON, A. B., Observations on demerol as obstetric analgesic. American Journal of Obstetrics and Gynecology, February 1943, 45, pages 320-326.
GLAZEBROOK, A. J.; BRANWOOD, A. W., Clinical trials of B-pethidine. Lancet, 27 October 1945, 2, pages 528-529.
GRIGORESCU, Dolantin in terapeutica durerii (Dolantin in therapy of pain), Romania Medical, Bucharest, 1 February 1941, 19, page 27.
GRUBER, C. M.; HART, E. R.; GRUBER, C. M., jr., The pharmacology and toxicology of ethyl ester of 1-methyl-4-phenylpiperidine-4-carboxylic acid (demerol), Journal of Pharmacology and Experimental Therapeutics, November 1941, 73, pages 319-334.
GUTTMAN, S. A., Demerol; caution in administration to patients with intracranial lesions, Journal of the American Medical Association, 15 January 1944, 124, pages 155-157.
HALL, J. E., Demerol for analgesia in obstetrics, Brooklyn Hospital Journal, January 1947, 5, pages 45-
HANSON, A.,6 (in Swedish) (Drugs of addiction: micromethods for their identification), Svensk Kemish Tidskrift, 1946, 58, pages 10-23.
HAZARD, R., Un nouvel analgésique synthetique pouvant servir de substitut la morphine. Le Progrés médical, 1944, 72, pages 289-292. Chimie et industrie, 1945, 54, page 421.
HECHT, H.; NOTH, P. H.; YONKMAN, F. F., Demerol: Clinical observations. Proceedings of the Central Society for Clinical Research, 1942, 15, page 89; also in Journal of the American Medical Association, 1943, 12l, page 1307.
6Ibid.
HELDT, T. J.; DALLIS, N. P.; O'CONNELL, W. J., Use of demerol in artificial fever, American Journal of Psychiatry, May 1945, 101, pages 789-792.
HEPBURN, J., Pethidine in asthma, British Medical Journal, 3 February 1945, page 174.
HEYDNER, W., Erfahrungen mit dem Spasmo-Analgetikum Dolantin bei Herzkranken. (Experiments in the use of the spasmo-analgesic dolantin in heart diseases), Fortschritte der Therapie, 1940, 16, pages 33-36.
HIMMELSBACH, C. K., Studies of addiction liability of "demerol", Journal of Pharmacology and Experimental Therapeutics, May 1942, 75, pages 64-68.
HIMMELSBACH, C. K., Further studies of addiction liability of demerol (1-methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester hydrochloride), Journal of Pharmacology and Experimental Therapeutics, September 1943, 79, pages 5-9.
HOBBS, F. B., Pethidine in asthma British Medical Journal, 2 September 1944, page 328.
HOFFMAN, R., Demerol, new departure in analgesia, evaluation of present therapeutic claims, Current Researches in Anesthesia and Analgesia, November-December 1943, 22, pages 336-340.
HOFFMAN, R., Demerol-report of experiences; new departure in analgesia, Journal of the Indiana Medical Association, March 1943, 36, pages 135-136.
HORI, C. G.; GOLD, S., Demerol in surgery and obstetrics; Canadian Medical Association Journal, December 1944, 51, pages 509-517.
HUFFORD, A. R., Gastroscopic preparation with demerol hydrochloride, The Review of Gastroenterology, September-October 1944, 11, pages 328-331.
HUNTER, C. A., jr.; HALE, R.; LORHAN, P. H., Demerol as preanesthetic agent, Journal of the Kansas Medical Society, March 1947, 48, pages 109-110.
IZAR, G.; LENZI, S., Studi sulla dolantin (Studies on dolantin), Rassegna Internazionale di Clinica e Terapia, Naples, 30 April 1941, 22, pages 251-256.
JACK, W. W.; TAYLOR, E. S., Edema of the uvula and glottis associated with demerol-scopolamine analgesia, American Journal of Obstetrics, 56, 1948, pages 587-589.
JESSEN, H., Dolantin, ved Haardnakket Hikke (Dolantin in therapy
7The original title of this work could not be located.
of incoercible hiccup), Ugeskrift for Laeger, Copenhagen, 27 November 1941, 103, page 1537.
JESSEN, H., Zur therapeutischen Anwendung von Dolantin (On the therapeutic use of dolantin), Deutsche medizinische Wochenschrift, 13 December 1940, 66, pages 1398-1399, also Ugeskrift for Laeger, Copenhagen, 12 December 1940, 102, pages 1326-1328.
JESSEN, H., Dolantin bei Singultus (Dolantin for hiccoughs). Deutsche medizinische Wochenschrift, 25 July 1941, 67, page 821.
KARATYGIN, V. M.; KALYABINA, Ob Obezbolibayus-hchem deyetbii lidola (Analgesic effect of lidol), Klinicheskaya Meditsina, Moscow, 1943 ,21, pages 63-67.
KARBER, G., Unterstellung von Dolantin, Pervitin und Benzedrin unter das Opiumgesetz (Control of dolantin, pervitine and benzedrine by the narcotics legislation), Zentralblatt für die gesamte Neurologie und Psychiatrie, 1942, 101, page 157, Deutsches Aerzteblatt, 1941, II., pages 260-262.
KEENAN, G. L., Microscopic identification of demerol, Journal of the American Pharmaceutical Association, 1946, 35, pages 338-339.
KEESER, E., Dolantin bei rheumatischen Gelenkerkrankungen (Use of dolantin in the therapy of rheumatical joint diseases), Medizinische Welt, 1941, 23, page 592.
KESARBANI, D. N., Gewöhnungsversuche mit Dolantin am Meerschweinchendarm (Experimental habituation of guineapig intestine to demerol), Naunyn Schmiedeberg's Archiv für experimentelle Pathologie und Pharmakologie ,1941, 198, pages 114-120. Zentralblatt für die gesamte Neurologie und Psychiatrie, July 1942, 102, page 204.
KIESSIG, H. J.; ORZECHOWSKI, G., Heber die analgetische wirkung des "Dolantins" (Analgesic action of dolantin), Schmerz, Narkose-Anaesthesie, August 1940, 13, pages 49-54, Chemische Zentralblatt, 1941, 1, page 3398.
KIESSIG, H. J.; ORZECHOWSKI, G., 7 (in German) (The central action of dolantin ), Schmerz, Narkose-Anaesthesie, 1941, 14, pages 41-47.
KIRTLAND, W. B., jr.; DEDENBACH, K., Status of demerol; its use in general surgery, Alexander Blain Hospital Bulletin, November 1946, 5, pages 178-185.
KLEIN, E. K., Erfahrungen mit Dolantin, einem myotrop und neurotrop wirkenden Spasmolytikum (Experi-ments with dolantin, a myotropic and neurotrope spasmolytic agent), Münchener medizinische Wochensc-hrift, 1939, II., page 1674.
KUCHER, I., Zwei Fälle von Dolantinsucht (Two cases of addiction to dolantin), Klinische Wochenschrift, 6 July 1940, 19, pages 688-689.
LANTUEJOUL, P., De l'emploi d'un nouvel analgésique au cours de l'accouchement, Le Progrés médical, 10 May 1942, 70, pages 211-212.
LARSON, E., The effect of pentobarbital sodium, evipal, sodium, and demerol on the action of insulin, Federation Proceedings, 1946, 5, page 189.
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LITTER, M.; TORINO, A., Estudios de farmacologia cuantitativa;.. curvas de la toxicidad de la dolantina (Studies of quantitative pharmacology; curves of toxicity of dolantin) , Revista del Instituto Bacteriologico, Buenos Aires, June 1943, pages 296-308.
LITTER, M.; TORINO, A., Curvas de toxicidad de la dolantin (Curves of toxicity of dolantin), La Semana Médica, Buenos Aires, 3 June 1943, pages 1247-1260, see abstract in English, Journal of the American Pharmaceutical Association (Scientific Edition), 194, 33, page 202.
LORANT, F., 8(in Hungarian) (Concerning addiction to dolantin), Orvosi Hetilap, Budapest 1942, page 235, Zentralblatt für die gesamte Neurologie und Psychiatrie, 1943, page 485.
LUBIT, E. C., Use of demerol hydrochloride in dentistry, Dental Items of Interest, 1949, 71, pages 814-817.
LUNGWITZ, W., Dolantinsucht und Dolantinsuchtige (Dolantin addiction and addicts), Psychiatrisch-neurologische Wochenschrift, Halle, 29 March 1941, 43, pages 139-142.
MacDONALD, A. D.; WOOLFE, G.; BERGEL, F.; MORRISON, A. L.; RINDERKNECHT, H., Analgesic action of pethidin derivatives and related compounds, British Journal of Pharmacology
8Ibid.
and Chemotherapy, March 1946, 1, pages 4-14.
McKENZIE, E. K., Pethidine in obstetrics, Lancet, 1943, 1, page 446.
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MANNING, G. W.; CAUDWELL, G. C.; The effect of demerol, ergotamine, and dihydro-ergotamine on mortality after coronary occlusion in dogs, British Heart Journal, April 1947, 9, pages 85-95.
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MEIDINGER, F., Action comparée sur la diurèse du chlorhydrate de morphine et du chlorhydrate de l'ester éthylique de l'acide 1-methyl-4-phenyl-piperidine-carbonique (dolosal), Comptes rendus des séances de la Société de biologie, 1945, 139, pages 396-397.
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.NOVARINI, E. F. L.; FELLNER, R., Sobre un caso de sendoacostumbramiento a la dolantina (A case of pseudo-habitation to dolantin), La Semana Médica, Buenos Aires, 27 August 1942, 2, pages 506-509.
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The original title of this work could not be located.
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________
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12The original title of this work could not be located.
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In the article on "The Evolution of the International Control of Narcotic Drugs" on page 11, the last paragraph but one should read: "The suppression of opium-smoking is now accepted..." and in the article "Unification of Conventions on Narcotic Drugs" (Official Section), the introductory sentence, page 26, should read: "Since the first international instrument...".