Bibliography

Sections

INTRODUCTION
Part I GENERAL AND REFERENCE WORKS
A
B
C
E
F
G
H
I
J
K
L
M
P
R
S
T
W
Part II OPIUM POPPY, OPIUM AND DRUGS MANUFACTURED THEREFROM A. OPIUM POPPY, OPIUM, AND PREPARED OPIUM
A
B
F
G
H
M
N
P
R
B. MORPHINE
A
B
C
D
E
G
H
I
J
K
M
N
R
S
T
W
C. OTHER DRUGS MANUFACTURED FROM OPIUM POPPY
A
B
C
E
F
G
H
K
M
P
R
S
T
V
W
Part III THE COCA LEAF AND DRUGS MANUFACTURED THEREFROM
B
D
F
G
H
M
P
S
W
Part IV CANNABIS AND CANNABINOL DRUGS
A
D
F
P
S
W
Part V THE SYNTHETIC DRUGS
C
D
F
G
H
K
L
P
R
S
V
W
B. DEMEROL - DOLANTINE - PETHIDINE - ISONIPECAINE - MEPERIDINE
B
C
D
F
H
L
M
O
P
R
S
T
W
C. AMIDONE--METHADONE--DOLOPHINE - "10820"
A
B
C
D
E
F
G
H
I
J
K
L
M
P
S
T
44 W
D. OTHER SYNTHETIC DRUGS
D
G
H
J
K
L
M
O
Part VI DRUG ADDICTION
A
B
D
E
F
H
I
L
M
O
P
S
W
Part VII MISCELLANEOUS WORKS
A
S

Details

Pages: 37 to 46
Creation Date: 1950/01/01

Bibliography

SCIENTIFIC PUBLICATIONS ON NARCOTIC DRUGS FOR 1949

INTRODUCTION

The following bibliography has been prepared by the Secretariat and includes scientific publications on narcotic drugs which appeared during 1949, as well as a few which appeared in 1948 but could not, for technical reasons, be included in our list for that year published in the Bulletin on Narcotics, vol. II, no. 1.

This bibliography has no claim to be complete, and information regarding books or articles not included in this bibliography would be gratefully received by the Division of Narcotic Drugs, Department of Social Affairs, United Nations Secretariat.

The bibliography has again been arranged by subject in the following fashion:

Part I. General and reference works;

Part II. Opium poppy, opium and drugs manufactured therefrom

A. Opium poppy, opium, and prepared opium

B. Morphine

C. Other drugs manufactured from the opium poppy;

Part III. The coca leaf and drugs manufactured therefrom;

Part IV. Cannabis and cannabinol drugs;

Part V. The synthetic drugs;

A. General works

B. Demerol-dolantine-pethidine-isonipecaine-meperidine

C. Amidone-methadone-dolophine-" 10820"

D. Other synthetic drugs;

Part VI. Addiction to narcotic drugs;

Part VII. Miscellaneous works.

Under each heading, publications are arranged alphabetically by author. Due to the nature of the sources available to the Secretariat for preparing this bibliography, several of the titles are given in translation only. They are preceded by an asterisk.

Part I GENERAL AND REFERENCE WORKS

A

ANONYMOUS: Estudio del cultivo de plantas medicinales en Chile (Study on cultivation of medical plants in Chile), Revista de Quimicay Farmacia , Santiago, 1949, 7, pp. 4-11.

ASHER, R.: A method of testing analgesics, Lancet,London, 1948, 2, pp. 771-773.

ASMUSSEN, E.; BOJE, O.: The effect of alcohol and some drugs on the capacity for work, Acta physiologica scandinavica, Stockholm, 1948, 15, pp. 109-113.

B

BERGEL, F.: The chemical constitution of drugs and their physiological activity, Manufact. Chem., London, 1948, 19, p. 36.

BERGER, F.: Opium. Segen der Arznei-Fluch des Suchtgiftes (Opium: blessing of medicine, curse of the addict), Universum, Vienna, 1948, 3, pp. 61-62.

BORRAS, P. E.; MUNOZ, J: M.: Algunos conceptos de la anestesia y la analgesia en cirugia ginecologica (Some concepts of anesthesia and analgesia in obstetrics), Revista mexicana de cirugia ginecologica y cancer, Mexico D.F., 1949, 17, pp. 39-44.

BRIEVA, A. J.:Concepto quimico farmaceutico de los medicamentos nuevos introducidos en los anos 1947-1948 (Chemical and pharmaceutical concept of new medicaments introduced during 1947:1948), Revista de Quimicay Farmacia, Santiago 1949, 7, pp. 4-14.

BROWN, D. V.; COOK, A. H.; HEILBRON, I.: Preparation of potential analgesic compounds. I., Journal of the Chemical Society, London, 1949 (Supplemental Issue N° 1), pp. 106-111.

C

COPEN, S. I.: Premedication by comedication in local anesthesia, American Journal of Orthodontics and Oral Surgery, St. Louis, April 1947, 33, pp. 290-300.

CULLEN, S. L.: The rational application of sedative and analgesic drugs, Journal of the Michigan State Medical Society, Lansing, 1949, 48/2, pp. 169-173.

E

EDDY, N. B.:Analgetika in der Krebstherapie (Analgesia in the treatment of cancer), Krebsarzt, Vienna, 1949, 4, p. 149.

EY, H.: L'emploi des substances narcotiques dans l'expertise medicolegale psychiatrique, Presse medicale, Paris, 1949, 57, p. 13.

F

FELDBERG, W.; LIN, R. C. Y.: The action of local anesthetics and of tubocurarine on the isolated intestine of the rabbit and guinea pig, British Journal of Pharmacology, London, 1949, 4, pp. 33-44.

FISCHER, R.; CHALUPA, L.: Detection of narcotics in biological material. Mikrochemie vereinigt mit mikrochimica Acta, Vienna, 1949, 34, pp. 257-268.

G

GAGNON, J.: Anesthesie, analgesie, amnesie en obstetrique, Union médicale, Montreal, 1949, 78, pp. 833-836.

GROSS, G. C.: Modern therapeutic agents, South Dakota Medical Journal, Sioux Falls, 1948, 1, p. 439.

GUICHARD, F.: Observations sur quelques expertises et recherches toxicologiques effectuees en Indochine, Annales pharmaceutiques francaises, Paris, October 1949, 7, pp. 615-620.

H

HEBB, C. D.; KONZETT, H.: The effect of certain analgesic drugs on synaptic transmission as observed in the perfused superior cervical ganglion of the cat, Quarterly Journal of Experimental Physiology, London, 1949, 35, pp. 213-217.

HELLIWELL, P. J.; HUTTON, A. M.: Analgesia in obstetrics, Anaesthesia, London, 1949, 4, pp. 18-21.

HENRY, T. A.: The Plant Alkaloids, J. A. Churchill, London, 1949, p. 804.

HEWER, A. J. H.; KEELE, C. A.: Analgesics, a method of testing in man, Lancet, London, 1949, 255, p. 683.

HEWER, A. J. H.; KEELE, C. A.: A clinical method of assessing analgesics, Lancet, London, 1949, pp. 431-435.

HOLLAND, M. O.: Current trends in modern medicinals, American Journal of Pharmacy, Philadelphia, November 1949, pp. 418-419.

HUGIN, W.: Zum heutigen Stand der Narkosefrage (Present state of the narcotic question), Helvetica chirurgica acta, Basel, 1949, 16, pp. 205-229.

I

IPSEN, J. I.: Biometric analysis of graded response with incomplete measurements in assays of analgesic drugs, Acta pharmacologica et toxicologica, Copenhagen, 1949, pp. 321-346.

J

JUNG, F.: Ueber Genussmittel und Genussgifte (Voluptuary and narcotic drugs), Studium gen., Heidelberg, 1948, 1, pp. 273-281.

K

KALLENBORN, V.: La lucha contra el trafico clandestino-de estupefacientes (The fight against the dandestine traffic in narcotic drugs), Revista de criminalogia, psiquiatda y medicina legal, Santiago, 1948, pp. 33-37.

L

LEHMAN, R. A.; KUPPERMAN, H. S.; PHILLIPS, J.: Studies on the relationship between chemical constitution and analgesic activity, Federation Proceedings, Washington, 1948, 7, pp. 237-238.

M

MARABUTO, P.: The fight against narcotics, International Criminal Police Commission, XVIIIth meeting, Bern, 10-15 October 1949, No. 8, Report by Mr. Mara-buto.

MORLOCK, G. A.: International co-operation relating to narcotic drugs, American Foreign Service Journal, 1949, 26, p. 26.

P

PERROT, E.: Les medicaments d'origine végétale en face des medicaments chimiques de synthèse, Journal de Pharmacie de Belgique, Brussels, 1949, 4, pp. 15-94.

PETER, Sister M.: Modern methods of minimizing pains during labor and childbirth, Journal of the American Association of Anesthetist Nurses, Chicago, 1948, 16, pp. 302-305.

PRASAD, S.: A brief historical survey of Indian drugs of vegetable origin, Journal of the American Pharmaceutical Association, Washington, 1949, 38, pp. 340-342.

PRESCOTT, F.; RANSOM, S. G.: Effect of analgesics on respiratory response to carbon dioxide in man, Lancet, London, !949, pp. 340-344.

R

RODRIGUEZ GARCIA, J. A.; PERDOMO, R. S.: Respuesta de la musculatura lisa de la piel aislada del perro a algunos farmacos (The action of some drugs on the smooth muscles of the skin of the dog), Archivos de la sociedad de biologia de Montevideo, 1948, 14, pp. 7-11.

S

SOEHRING, K.; BECHER, F.: Ueber die Messung analgetischer Wirkung im Tierver-such (Measurement of the analgesic action in experimentation on animals), Archives Internationales de Pharmacodynamie et de Thérapie, Ghent, 1949, 79, pp. 45-69.

T

TEUCHMANN, J. K.: Z badan doswiadczalnyck nad pemkten uchwytu dzialania srodkow odurza jacych (Research in central localization of narcotics), Polski tygodnik lekarski, Warsaw, 1949, 4, pp. 417-422.

W

WATTS, D. Y.: The effect of local anesthetics on the respiration of brain homogenates, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 96, pp. 325-331.

Part II OPIUM POPPY, OPIUM AND DRUGS MANUFACTURED THEREFROM A. OPIUM POPPY, OPIUM, AND PREPARED OPIUM

A

ALKALOIDA VEGYESZETI GYAR RESZVENTARSASAG (Opium alkaloids from dry poppy straw), British Patent 623907, 25 May 1949.

B

BENCZE, B.; HALMY, J. B.: Poppies, Magyar: Kemikusok Lapja, Budapest, 1948, 3, pp. 570-576.

F

FIELDS, A.: Opium, Merck Report, Rahway, New Jersey, 1949, 58/2, pp. 4-8.

G

GSTIRNER, F.; VOLLMER, K.: Die Bestimmung des Morphins in getrockneten Mohnkapseln (Determination of morphine in dried poppy capsules), Süddeutsche Apotheker Zeitung, Stuttgart, 1949, 89, pp. 167-171.

H

HEEGER, E. F.; POETHKE, W.: Papa-vet somniferum L. Der Mohn, Anbau,. Chemie, Verwendung (Papaver somniferum L. the poppy: culture, chemistry, uses), Werner Sanger, Berlin, 1948, 2nd Ed., 105 pp.

M

MANSKE, R. H. F.: The alkaloids of the papaveraceous plants; XLII. Dentromecon rigida Benth, Canadian ]ournal of Research,'Ottawa, 1949, 27B, pp. 653-654.

MASCRE, M.; GENOT-BOULANGER, Ch.: Dosage de la morphine dans les capsules de pavot, Annales pharmaceutiques francaises, Paris, 1949, 7, pp. 493-502.

N

NEUFELD, O. E.; ROSENBLUM, E. I.: The estimation of morphine in opium poppy, Australian Chemical Institute, Journal and Proceedings, Melbourne, 1949, 16, pp. 252-254.

P

PHU, L. Q.; TRONG, L. Q.; DUQUENOIS, P.: La fumee de chandou indochinois et sa teneur en morphine, Annales de medecine legale, criminologie, police scientifique, medecine sociale, et toxicologie, Paris, 1949, 29, p.p. 192-195.

POETHKE, W.; ARNOLD, E.: Ueber die Bestimmung des Morphins in Mohnkapseln (On the determination of morphine in poppy capsules), Pharmazeutische Zentralhalle, Leipzig. 1949, 88, pp. 1-5.

R

ROSENTHALER, L.; KOCAK, H.: Einige Einzelheiten fiber das tiirkische Opium (Some particularities of Turkish opium), Schweizerische Apotheker-Zeitung, Zurich, 1949, 87, pp. 141-145.

B. MORPHINE

A

ABOOD, L. G.; KUN, E.: In vitro oxydation of morphine by tissue homogenates, Federation Proceedings, Baltimore, 1949, 8, p. 270.

ABREU, B. E.; ELLIOTT, H. W.; SUTH-ERLAND, V. C.; MARGOLIS, L.; SIMON, A.: Effect of morphine sulfate on cerebral blood flow and metabolism in man, Federation Proceedings, Baltimore, 1949, 8, p. 270.

ANONYMOUS: Morphine, Pharmaceutical Journal, London, 1949, 108, p. 451.

ANONYMOUS (Correspondence): Comments on the antidiuretic action of morphine, American Journal of Obstetrics and Gynecology, St. Louis, Missouri, October, 1949, 58, p. 825.

B

BENNETT, H. A.; GRAY, C. E.; CULLEN, S. C.: The effects of large doses of barbiturates and morphine and scopolamine on respiratory minute volume exchange, Anesthesiology, Lancaster, Pennsylvania, 1949, 10, pp. 548-552.

BLONDET, P.; BUFFARD, P., et 'al.: La morphine par voie buccale en radiologie digestive, Journal de radiologie et d'electrologie, Paris, 1949, 30, p. 45.

BROWN, W. E.; HODGES, R.; BRAD-BURY, J. T.: Effects of morphine on renal clearances of para-amino hippurate and sodium thiosulfate in the human kidney, American Journal 'of Medicine, New York, 1949, 6, p. 663.

C

CHRISTENSEN, E. M.; GROSS, E. G.: Efecto analgesico comparativo de la morfina, la meperidina y el metadon (translation) (Comparative analgesic effects of morphine, meperidine and methadone), America clinica, New York, 1948, 13, pp. 414-417.

CRAMER, J. S. N.; VOERMAN, J. G.: Colorimetric determination of morphine, Pharmaceutisch Weekblad, Amsterdam, 1949, 84, pp. 129-133.

D

DAUBER, CEPERO, R.: Metodo de absorcion lenta de la codeina y morfina en el tratamiento del dolor en el cancer, yen el pre y post-operatorio (Method for slow absorption of codeine and morphine in the treatment of cancer pains, as well as before and after operations), Dia medico, Buenos Aires, 1949, 21, pp. 1501-1504.

DOGLIOTTI, M.: La formula leucocitaria nei pomfi allergici e da morfina (The leucocitary formula of allergic eruptions due to morphine), Dermosifilografo, Turin, 1949, 24, p. 111.

E

ELLIOTT, H. W.; SUTHERLAND, V. C.; BOLDREY, E. B.: Respiration of human brain slices and the effects of morphine and methadone on oxygen uptake, Federation Proceedings, Baltimore, 1949, 8, pp. 288-289.

EWING, C. D.; MAGILL, L. J.: Survey of U.S.P. XIV and N.F. IX codeine and morphine monographs, Bulletin of the National Formulary Committee, Washington, D. C., 1949, 17, pp. 169-173.

G

GATES, M. D. Jr.; NEWHALL, W. F.: The synthesis of ring systems related to morphine. III. The carbon-nitrogen ring system, Experientia, Basel, 1949, 5, pp. 285-286.

GLANZMANN, S.: Influence of morphine on the sensitivity of 'the skeletal muscle of the frog to acetylcholine and potassium,* Farmacoterapia actual, Madrid, 1949, 6, pp. 23-24.

GOTO, K.: Advances in the syntheses of morphine alkaloids, Journal of the Pharmaceutical Society of Japan, Tokyo, 1949, 69, pp. 107-113.

GREWE, R: The problem of morphine synthesis (translation) United Nations document E/CN.7./154, 6 May 1949, 2 pp.

GRIFFITHS, W. J. Jr.; COHEN, M.: Effects of morphine Sulphate and diaminon hydrochloride on incidence of audiogenic seizures of albino rats, Journal of Comparative Physiological Psychology, Baltimore, 1949, 42, pp. 391-397.

H

HEBB, C. O.; KONZETT, H.: Difference between morphine and synthetic analgesics in their actions on ganglionic transmission, Nature, London, 1949, 163, pp. 720-721.

HORNING, E. C.; SCHOCK, R. V. Jr.: Morphine studies. The synthesis of a tetra-linpiperidine fused ring system, Journal of the American Chemical Society, Rochester, New York, 1949, 71, pp. 1359-1362.

HOUGS-OLSEN, W.: Comparative investigations into the analgesic effects of morphine and dl-6-dimethylamino-4,4-di-phenyl-3-heptanone hydrochloride, Acta phar-maeologica et toxicologica, Copenhagen, 1949, 5, pp. 33-34.

HUGGINS, R. A.; HANDLEY, C. A.; LAFORGE, M.: Effects of morphine, codeine, and dilaudid on blood flow, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 95, pp. 318-321.

I

IGLAUER, H.: The determination of morphine in the urine, Angewandte Chemic, Heidelberg, 1949, 61, pp. 412413.

J

JENSEN, V. G.: Farmaceutisk-kemisk vurdering af morfm-skopolaminoplosning (Pharmaceutical-chemical estimation of mor-phine-scopolamine solutions), Dansk Tids-skrift for Farmaci, Copenhagen, 1949, 23, pp, 192-194.

K

KEENAN, G. L.: Microscopic identification of morphine, Chemist-Analyst, Phillips-burg, New Jersey, 1949, 38, pp. 59-62.

It has not been possible to obtain the original title of this article.

KRAUSHAAR, O. F.; BRADSBURY, J. T.; WANG, Y. K.; BROWN, W. E.: Morphine suppression of urinary output in pregnant and non-pregnant women, American Journal of Obstetrics and Gynecology, St. Louis, Missouri, 1949, 57/2, pp. 302-311.

KUN, E.; ABOOD, L. G.: In vivo action of morphine, methane and phenobarbital on the glycogen synthesis from glucose in the rat liver, Archives internationales de pharmacodynamie et de therapie, Ghent, 1949, 80/I, pp. 51-61.

M

MACDONALD, A. D.: Analgesics: Some developments, Journal of Pharmacy and Pharmacology, London, 1949, 1, pp. 569-575.

MERENDINO, K. A.: Pharmacologic aspects of gastric secretion; effects of opium alkaloids and "allied" drug demerol on gastric secretions in man, Gastroenterology, Baltimore, March 1948, 10, pp. 522-531.

N

NAGAY, Y.: Syoni ni taisuru morphine tyusya no oyo ni tuite (Use of morphine injections with children), Acta pediátrica Japonica, 1948, 52, p. 5.

R

RABBONI, F.; GRAMIGNANI, V: Uso endovenoso della morfina in preanestesia ed in chirurgia toracica (The endoveinous use of morphine in thoracis pre-anesthesia and surgery), Sicilia med., 1949, 6, pp. 296-302.

S

SAN MARTIN CASAMADA, Ramon; MOSQUEIRA TORIBIO, Arturo: (Colorimetric determination of morphine),* Anales de la real academia de farmacia, Madrid, 1948, 14, pp. 433-444; 1949, 15, pp. 343-348.

SANTA CRUZ, F.; DERIU, G.: L'impiego della morfina per via parenterale nella studio del tubo digerente (The parenteral use of morphine for the study of the digestive tube), Riv. chir. med., Parma, 1949, 1, pp. 39-60.

SAUTER, H.: Einfluss des Morphium und dessen Kombination mit Dihydroergotamin auf Uterus und den Geburtsverlauf (Influence of morphine and of its combination with dihydroergotamin on the uterus and the confinement), Gynaecologia, Basel, 1949, 128, pp. 77-100.

SCHAUMANN, O.: (The analgiphoric group in morphine),* Die Pharmazie, Berlin, 1949, 4, pp. 364-365.

SCHUMANN, O.: Morphium (Morphine), Deutseher Apotheker Verlag, Berlin, 1949, 288 pp.

SCHUSTER, G.; LORY y DALIPHAR, R.: (Injection solutions of morphine),* Farmalecta, Buenos Aires, 1949, 4, pp. 107-108.

SHIDEMANN, F. E.: Influence of chronic morphine poisoning on growth and metabolism of the albino rat, Proceedings of the Society for Experimental Biology and Medicine, Utica, New York, 1949, 71, pp. 38-40.

STOLMAN, A.; STEWART, C. P.: Separation and determination of mixtures of morphine, heroin, codeine, and barbiturates by adsorption, Analyst, Cambridge, England; 1949, 74, pp. 543-546.

STOLMAN, A.; STEWART, C. P.: Isolation and determination of morphine, codeine, and heroin from viscera and body fluids by adsorption, Analyst, Cambridge, 1949, 74, pp. 536-542.

T

THORN, N.; ALGREN, Allen: Quantitative determination of pseudo-morphine in morphine, Svensk Farmaceutisk Tidskrift, Stockholm, 1949, 53, pp. 17-24.

W

WATTS, D. T.: Inhibition of succinic oxidase system by meperidine, methadon, morphine, and codeine, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 95, pp. 117-121.

WEISS, U.; WEINER, N.: The isomerization. of morphine to O-desmethylthebainone, Journal of Organic Chemistry, Baltimore, 1949, 14, pp. 194-203.

C. OTHER DRUGS MANUFACTURED FROM OPIUM POPPY

A

ANGULO CARPIO, M. D.: Ensayos sobre la accion C-mitotica de algunos alcaloides del opio en comparacion con la producida pot la colchicina (Assays on the C-mitotic action of some opium alcaloicls compared with the action produced by colchicine), Farmacognosia, Madrid, 1948, 7, pp. 83-102.

AOKI, S.; SATO, T.: Syoni yakuyo-rijo ni tnite; codeine no rinsyo zikken (On the subject of doses of drugs for the childreni clinical experiments with codeine), Acta. paediatrica Japonica, 1948, . 52, p. 38.

AWE, W.; DEMELIUS, F.: Reaction of some opium alkaloids and morphine derivative with iodic acid),* Süddeutsche Apotheker Zeitung, Stuttgart, 1949, 89, p. 598.

B

BORNMANN, Gerhard; LOESER, Arnold: Experimentelle Studie zur Darmwirksamkeit des Papaverin (Action of papaverine on the intestine), Archives internationales de pharmacodynamie et de thérapie, Ghent, 1949, 79, pp. 332-335.

C

CASPARIS, P.; KUHNI, E.; LEINZINGER, E.: Ueber einige Kodeinglykoside (On some codeine glucosides), Pharmaceutica acta helvetiae, Zurich, 1949, 24, pp. 145-155.

CLAYSON, David B.: Reduction of cotarnine and certain derivatives thereof. Journal of the Chemical Society, London, 1949, pp. 2016-2019.

CORTI, R. N.; GUILLOT, C. F.: La papaverina en el tratamiento del prurito (Papaverine in the treatment of prurience), Prensa medica argentina, 1949, 36, p. 883.

E

EDDY, N. B.: Metopon hydrochloride. An experiment in clinical evaluation, Public Health Reports, 1948, 64, pp. 93-103.

F

FARMILO, C. G.; LUCAS, G. W. H.: Studies on the identification of narcotics Microchemical reactions for identification of metopon, Journal of the American Pharmaceutical Association, Washington, 1949, 38, pp. 491-495.

G

GITTNER, H.: Cien afios de papaverina (One hundred years of papaverine), Monitor de la farmacia y de la terapeutica, Madrid, 1949, 55, pp. 123-125.

GREWE, R.; MONDON, A.; NOLTE, E.: Total synthesis of tetrahydrodesoxycodeine. Annales der Chemie; Justus Liebigs, Berlin, 1949, 564, pp. 161-198.

GRIFFON, Henri; PERONNET, Marcel: Recherche et dosage de faibles quantites de codeine dans un sirop compose Annales pharmaceutiques francaises, Paris, 1949, T.VII, 12, pp. 705-708.

H

HERTZ, M.: Ancigteodem ved codein-for-giftning (Facial swelling in cases of codeine poisoning), Nordisk Medicin, Stockholm, 1949, 41, p. 992.

K

KISELEV, V. V.; KONOVALONA, R, A.: Zhurnal Obshchei Khimii (Alkaloids of papaveraceous family. Structure of isothebaine),* ( Journal of General Chemistry), Moscow, 1949, 19, pp. 148-156.

M

MERCIER, Fernand; MERCIER, Jacques et Marie; SESTIER, R.: Action Spasmolytique de certains derives carboxyliques de la papaverine et de la dihydro papaverine, Comptes rendus de la Societe de Biologie, Paris, 1949, 143, pp. 92-94.

MONROE, M. W.: Medical pain relief; clinical observations of a morphine derivative, metopon hydrochloride, Marquette Medical Review, Milwaukee, 1949, 14/2, p. 53.

MORSIER, G. de; FELDMANN, H.: Le traitement de l'alcoolisme chronique par l'apomorphine; etude portant sur 100 cas. Revue Medicale Suisse romande, Lausanne, 1949, 69, pp. 417-439.

MUKHOPADHYAY; PARTHSARA-THY, C.: Papaverine from Indian opium, Journal of Scientific and Industrial Research (India), Delhi, 1949; 8b, No. 1, pp. 22-23.

P

POWERS, B. R.: Use of methadon to combat withdrawal symptoms of dilaudid addiction; case report, Journal of Tennessee State Medical Association, Nashville ,Tennessee, 1949, 42, p. 83.

R

REDEL, J.; BOUTEVILLE, A.: Les esters de papaverine et acides norpapaverine et le diethylammoethanol: Bulletin de la Societe Chimique de France, Paris, 1949, pp. 443-446.

REDEMANN, C. E.; WISEGARVER, B. B.; ALLES, G. A.: Characterization of certain alkaloids from Fagara coco, Journal of the American Chemical Society, Washington, 1947, 71, pp. 1030-1034.

RUSSEK, H. I.; ZOHMAN, B. L.: Papaverine in epilepsy, New York State Journal of Medicine, New York, 1949, 49, p. 1315.

S

SCHNIDER, O.; GRUSSNER, A.: Synthese von oxy-morphinanen (Synthesis of hydroxy-morphinanes), Helvetia Chimica Acta, Basel, 1949, 32, pp. 821-828.

SCHUELER, F. W.; GROSS, E. G.; HOLLAND, H.: Morphine derivatives: chemical constitution and analgesic action, Journal of the American Pharmaceutical Association, Washington, 1949, 38, pp. 74-81.

SIMON, A. J.; DOLGIN, M. and others: A re-evaluation of papaverine in the treatment of angina pectoris, Journal of Laboratory and Clinical Medicine, St. Louis, Missouri, 1949, 34, pp. 992-997.

T

TSATSAS, Georges: Sur la synthese d'un isomere de la Papaverine (dimethoxy-2-3 benzyl) -1 dimethoxy-5-6- isoquinolenie), Annales pharmaceutiques francaises, Paris, 1949, T.VII, 12, pp. 733-748.

V

VOIGT, Paul G.: Papaverin (Papaverine), Die Pharmazie, Berlin, 1949, 4, pp. 1111-1114.

W

WEYLARD, J.; TISCHLER, M.: Methylvanillin from opianic acid, U.S. Patent 2477158, 26 July 1949.

Part III THE COCA LEAF AND DRUGS MANUFACTURED THEREFROM

B

BODENDORF, K.; KRUGER, K. V.; ZERMAL, F.: (A group of new local anesthetics resembling cocaine),* Annalen der Chemie, Justus Liebigs, Berlin, 1949, 562, pp. 1-14.

D

DE JONG, A. W. K.: (A complete extraction of the bases and the acid esters of l-norecgonine from coca leaves),* Recueil des travaux chimiques des Pays-Bas, Amsterdam, 1949, 68,.pp. 138-140.

DRUDE, W.: (Adulteration of cocaine),* Siiddeutsche Apotheker-Zeitung, Stuttgart S., 1949, 89, pp. 277-278.

F

FEISSLY, R.; LUDIN, H.: Action de la cocaine sur les plaquettes sanguines, Helvetica physiologica et pharmacologica acta, Berne, 1949, 7, C.9.

G

GASTALDI, E.: Produzione industriale di cocaina (Industrial production of cocaine), Bollettino chimico farmaceutico, Milan, 1949, 88, pp. 175-188.

GUTIERREZ NORIEGA, C.: Study of coca addiction, Federation Proceedings, Baltimore, 1949, 8, p. 298.

GUTIERREZ NORIEGA; C.: El habito de la coca en el Peru (The habit of coca chewing in Peru), America Indigena, Mexico, 1949, 9, pp. 143-154.

H

HUCKNALL, E.; TURFITT, G. E.; The identification of local anesthetic drugs of the benzoic ester group, The Journal of Pharmacy and Pharmacology, London, 1949, 1, pp. 462-469.

M

MARIN AMAT, M.: La cocaina, sustancia utilizada en terapeutica ocular (Cocaine: its use in ocular therapeutics), Archivos de la Sociedad oftalmoldgica hispano-americana, Madrid, 1949, 9, pp. 931-933.

P

PAZ SOLDAN, C. E.: La coca y el prestigio del Peru (Coca and the prestige of Peru), Reforma Medica, Lima, 1949, 35, pp. 5-8.

S

STEINHAUS, J. E.: Cocaine-barbiturate antagonism, Federation Proceedings, Baltimore, 1949, 8, pp. 333-334.

W

WALLIS, G. G.: A case of hallucinosis due to cocaine, Journal of the Naval Medical Service, London and New York, 1949, 35, p. 112.

Part IV CANNABIS AND CANNABINOL DRUGS

A

ADAMS, R.; HARFENIST, M.; LOEWE, S.: New analogs of tetrahydrocannabinol. XIX., Journal of the American Chemical Society, Washington, D. C., 1949, 71, pp. 1624-1628.

D

DAVIS, J. A.; RAMSEY, H. H.: Anti-epileptic action of marihuana-like substances, Federation Proceedings, Baltimore, 1949, 8, pp. 284-285.

F

FRASER, J. D.: Withdrawal symptoms in cannabis-indica addicts, Lancet, London, 1949, 2, p. 747.

P

PARIS, R.; MERAC, M. L. du: Teneur en resine et activite physiologique de chanvre cultive dans la region parisienne, Annales pharmaceutiques francaises, Paris, 1949, 7, pp. 47-51.

S

SUSSANNA, V.: (Pharmacological activity of alcohol and ether extracts of Indian cannabis cultivated in the Naples Botanical Garden),* Bollettino della Societa italiana di biologia sperimentale, Naples, 1949, 24, pp. 668-670.

W

WOLFF, P. O.: La marihuana en la America Latina; la amenaza que constituye (Marihuana in Latin America; the threat it constitutes), Revista de la Asociacion Medica Argentina, Buenos Aires, 1948, 62, pp. 747-762.

WOLFF, P. O.: Marihuana in Latin America, the Threat It Constitutes. Linacre Press, Inc., Washington, D. C., 1949.

Part V THE SYNTHETIC DRUGS

A. GENERAL WORKS

C

CHAPIN, M.: The newer drugs, Journal of the Maine Medical Association, Portland, Maine, 1949, 40, pp. 40-42.

COSTELLO, C.; McDONALD, J.: The role of a new analgesic in surgery, Journal of the Missouri State Medical Association, St. Louis, Missouri, 1949, 46, pp. 333-337.

D

DUFRESNE, R. R.: Les medicaments nouveaux, Canadian Nurse, Montreal, 1949, 45, pp. 127-129.

F

FOSTER, R. H. K.; DEBOER, B.: Respiration apparatus for rabbits and its use in the study of piperidine analgesics, Federation Proceedings, Baltimore, 1949, 8, p. 292.

G

GROSS, E. G.; BROTMAN, M. A.; NAGYFY, S. F.; SAUTELLE, W. W.; ZAGER, L. I.; New potent analgesic agent, Federation Proceedings, Baltimore, 1949, 8, p. 297.

H

HEBB, C. O.; KONZETT, H.: Difference between morphine and synthetic analgesics in their actions on ganglionic transmission, Nature, London, 1949, 163, pp. 720-721.

HOLLAND, H. L.; GROSS, E. G.: Two new analgesics, Federation Proceedings, Baltimore, 1948, 7, pp. 227-228.

K

KIRCHHOF, A. C.: Further studies on synthetic analgesics, Federation Proceedings, Baltimore, 1948, 7, p. 234.

L

LEWIS, J. R.: Development of tolerance in rats to some new synthetic analgesics, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 96, pp. 31-37.

LEWIS, J. R.: Tolerance in rats to new synthetic analgesic drugs, Federation Proceedings, Baltimore, 1949, 8, pp. 315-316.

P

PFEIFFER, C. C.; SANTOS-MARTINEZ, J.; SHERROD, T. R.: The nature of the prosthetic groups of analgesics and their possible action as blocking agents, Federation Proceedings, Baltimore, 1948, 7, pp. 248-249.

R

ROBSON, J. M.; NISSIM, J. A.: The new analgesics, Chemical Products, London, 1949, 12, pp. 284-292.

S

SEEVERS, M. H.: Pharmacology of the newer synthetic analgesics, Journal of Oral Surgery, Ann Arbor, Michigan, 1949, 7/I, pp. 30-38 (16).

SMITH, Austin, (editor): New and non-official remedies, J. B. Lippincott Co., Philadelphia, 1949, 805 pp.

SMITH, A.: Safeguards in the use of new drugs, Bulletin of the New York Academy of Medicine, New York, 1949, 25, pp. 115-124.

SMITH, E. J.; NAGYFY, S. F.: A report on comparative studies of newer drugs used for obstetrical analgesia, American Journal of Obstetrics and Gynecology, St. Louis, Missouri, 1949, 58, p. 695.

SOFFER, M. D.; CAVAGNOL, J. C.; GELLERSON, H. E.: Syntheses in the direction of morphine. I. 7-methoxy- and 7, 8-dimethoxy- 3, 4- dihydro-2 (1H) - naphthalen-one, Journal of the American Chemical Society, Washington, D. C., 1949, 71, p. 3857.

V

VAN DYKE, H. B.: New analgesic drugs, Bulletin of the New York Academy of Medicine, New York, 1949, 25, pp. 152-175.

VAN DYKE, H. B.: Synthetic analgesic drugs, American Journal of Medicine, New York, 1949, 6, pp. 681-683.

W

WATTS, D. T.: Inhibition of succinic oxidase system by meperidine, methadon, morphine, and codeine, Journal of Pharmacology and Experimental Therapeutics, Baltimore 1949, 95, pp. 117-121.

WAYNE, E. J.: Los analgesicos mas modernos (The most modern analgesics), Jornada medica, Buenos Aires, 1949, 3, pp. 221-226.

B. DEMEROL - DOLANTINE - PETHIDINE - ISONIPECAINE - MEPERIDINE

B

BROTMAN, M.; CULLEN, S. C.: Supplementation with demerol during nitrousoxide anesthesia, Anesthesiology, Philadelphia, 1949, 10, p. 96.

BROWN, J. M.; VOLPITTO, P. B.; TORPIN, R.: Intravenous demerol-scopolamine amnesia during labor, Anesthesiology, Philadelphia, 1949, 10, pp. 15-24.

C

CAPRARO, V.: (Comparison of the spasmolytic action of dolantin and of new compounds of analogous action),* Farmaco scienza e tecnica, Pavia, Italy, 1948, 3, pp. 137-144.

CARMICHAEL, E. B.; JOHNSON, W. H.; KAY, F. A.: Toxicity studies with demerol hydrochloride (isonipecaine) on adult male guinea pigs, Federation Proceedings, Baltimore, 1949, 8, p. 190.

CHRISTENSEN, E. M.; GROSS, E. F.: Efecto analgesico comparativo de la morfina, la meperidina y el metadon (Comparison of the analgesic effects of morphine, meperidine and methadon), America clinica, New York, 1948, 13, pp. 414-417.

CLIMENKO, D. R.; BERG, H.: Influence of demerol on contractions of ureter, Journal of Urology, Baltimore, 1949, 43, pp. 255-258.

D

DUTTA, N. K.: Some pharmacological properties common to atropine, pethidine, procaine, and quinidine, British Journal of Pharmacology and Chemotherapy, London, 1949, 4, pp. 197-201.

F

FLIPSE, M. E.; FLIPSE, M. J.: Hyper-pyrexia due to demerol, Southern Medical Journal, Birmingham, Alabama, 1949, 42, pp. 395-401.

H

HARNING; SCHOCK, R. U. Jr.: Morphine studies. The synthesis of a tetralinpiperidine fused ring system, Journal of American Chemical Society, Rochester, New York, 1949, 71, pp. 1359-1362.

L

LEWIS, J. R.: A study of the development of tolerance to the actions of 1-methyl-4-(3-hydroxy-phenyl)-4-piperidyl ethyl ketone hydrochloride in dogs, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 96, pp. 410-415.

LUBIT, E. C.: Use of demerol hydrochloride in dentistry, Dental Items of Interest, Brooklyn, New York, 1949, 71, pp. 814-817.

M

MERENDINO, K. A.: Pharmacological aspects of gastric secretion; effect of opium alkaloids and "allied" drug demerol on pouch secretions in dogs, Gastroenterology,Baltimore, 1948, 10, pp. 504-511.

MUSHIN, W. W.; RENDELL-BAKER, L.: Pethidine as a supplement to nitrous oxide anaesthesia, British Medical Journal, London, 1949, 2, p. 472.

O

O'REILLY, P. J.: Pethidine in obstetrics; review of 153 cases, Lancet, London ,1948, 2, p. 1012.

P

PICKERING, R. W.; ABREU, B. E.; BOHR, D. F.; REYNOLDS, W. F.: Some effects of meperidine on gastro-enteric, extra-hepatic biliary, and cardiovascular activity, Journal of the American Pharmaceutical Association, Washington, D. C., 1949, 38, pp. 188-192.

R

RUSTIA, G.; ALMEDA, L.: Demerol and scopolamine in obstetrics, Journal of the Philippine Medical Association, Manila, February. 1948, pp. 61-65.

S

STEELE, C. W.: A comparison of the antidiuretic effect of demerol and of methadon diuresis in congestive heart failure; a case report, Journal of the Maine Medical Association, Portland, 1949, 40, pp. 277-281. 281.

STRAZZA, J. A. Jr.: Demerol and barbiturate poisoning, Journal of the Medical Society of New Jersey, Trenton, New Jersey, 1949, 46, pp. 136-138.

T

TAINTER, M. L.: Estudio comparativo de algunas acciones del demerol y del methadon (Comparative study of some aspects of the action of demerol and methadon), Boletin de la Asociación de médica de Puerto Rico, San Juan, P. R., 1948, 40, pp. 1-14.

TAINTER, M. L.; BUCHANAN, O. H.: A comparison of .certain actions of demerol and methadone, California and Western Medicine, San Francisco, 1949, 70, pp. 35-43.

THORP, R. H.; WALTON, E.: Search for new analgesics. Part II. Further homologues of pethidine and the pharmacology of these and other components, Journal of the Chemical Society, London, May 1948, pp. 559-561.

W

WAY, E. L.; GIMBLE, A. I.; McKELWAY, W. P.; ROSS, H.; SUNG, C. Y.; ELLSWORTH, H.: The absorption, distribution, and excretion of isonipecaine, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 96, pp. 477-484.

WOLFF, P. O.: On pethidine and methadone derivatives, Bulletin of the World Health Organization, Geneva, 1949, 2, pp. 193-204.

C. AMIDONE--METHADONE--DOLOPHINE - "10820"

A

ANSLINGER, H. J.: Methadon addiction (correspondence), Journal of the American Medical Association, Chicago, Illinois, 1948, 138, p. 609.

ATTENBURROW, J.; ELKS, J.; HEMS, B. A.; SPEYER, K. N.: Analgesics; the synthesis of amidone and some of its analogues, Journal of the Chemical Society, London, February 1949, pp. 510-518.

B

BATTERMAN, R. C.; OSHLAG, A. M.: The effectiveness and toxicity of methadon, a new analgesic agent, Anesthesiology, Philadelphia, 1949, 10, pp. 214-222.

BECKER, J.; WULFF, K. J.: Klinische Erfahrungen mit dem Analgeticum Amidon "Hochst" (Clinical experiments with the analgesic Amidon "Hochst"), Medizinische Klinik, Berlin and Vienna, 1949, 44, pp. 705-707.

BERGE, E.; MULLER, H.: Narcosis of dogs with polamidone, Tierarztliche Umschau, Constance, Germany, 1949, 4, pp. 372-377.

C

CHENEY, L. C.; SMITH, R. R.; BINKLEY, S. B.: Ketimines and acylketimines related to amidone, Journal of the American Chemical Society, Rochester, New York, 71, pp. 53-56.

COUNCIL ON PHARMACY AND CHEMISTRY: Methadon, generic term for 6-dimethylamino-4,4-diphenyl-3-heptanone. Later changed to methadone, Journal of the American Medical Association, Chicago, Illinois, 1947, 134, p. 1483,·1948, 138, p. 651.

CUSIC, J. W.: Improvement on the process for making amidone, Journal of the American Chemical Society, Rochester, New York, 1949, 71, p. 3456.

D

DUPRE, D. J.; ELLIS, J.; HEMS, B. A.; SPEYER, K. N.; EVANS, R. M.; ATTEN-BURROW, J.: Analgesics. I. Esters and ketones derived from α-amino-ω-cipruo-ωω-diaryl-alkanes. II. The synthesis of amidone and some of its analogues, Journal of the Chemical Society, London, 1949, 2, pp. 500-518.

E

EHRHART, G.; SCHAUMANN, O.: Polamidon, ein neues, stark wirkendes Analgetikum (Polamidone, a new powerful analgesic), Medizinische Monatsschrift, Stuttgart, 1949, 3, pp. 605-606.

EISENBRANDT, L. L.; ELLIOTT, H. W.: Comparative in vivo and in vitro effect of methadone upon the Q 02 of rat liver, kidney, and jejunum, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 97, pp. 120-124.

EISENBRANDT, L. L.; ABDOU, I. A.; ADLER, T. K.: Biliary excretion and intestinal reabsorption of C14-labeled methadone hydrobromide, Federation Proceedings, Baltimore, 1949, 8, p. 288.

ELLIOTT, H. W.; CHANG, F. N. H.; ABDOU, I. A.; ANDERSON, H. H.: The distribution of radioactivity in rats after administration of C14-labeled methadone, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 95, pp. 494-501.

F

FLATAKER, Lars; WINTER, C. A.: Comparison of heptazone (4,4-diphenyl-6-morpholinoheptanone-3-hydrochloride) with other analgesic drugs, Federation Proceedings, Baltimore, 1949, 8, p. 47.

FULTON, C. C.: The identification of methadon by microcrystals, United Nations document, E/CN.7/117, 14 April 1948, pp.17-31.

G

GINSBURG, D.; BAIZER, M. M.: Fluorene analog of amidone, Journal of the American Chemical Society, Rochester, New York, 1949, 71, p. 1500.

GLAZEBROOK, A. J.: Clinical trials of analgeticum NU 896 and of amidone, Edinburgh Medical Journal, Edinburgh, 1949, 56, pp. 206-213.

GREIG, M. E.: The inhibition of hexokinase by amidone (2-dimethyl-amino-4,4-diphenylheptanone - 5 - hydrochloride ), Archives of Biochemistry, New York, 1948, 17, pp. 129-137.

GREIG, M. E.; HOLLAND, W. C.: Effect of the D- and L-isomers of isoamidone on the permeability of dog erythrocytes, Proceedings of the Society for Experimental Biology and Medicine, New York, 1949, 71, pp. 189-192.

GREIG, M. E.; HOWELL, R. S.: The inhibition by amidone 1, 3 of pyruvate and succinate oxidation by rat brain and the reversal of the inhibition by boiled yeast extract, Archives of Biochemistry, New York, 1948, 19, pp. 441-448.

H

HENDERSON, F. G.; ROBBINS, E. B.; CHEN, K. K.: Action and toxicity of methadone in various animals, Archives internationales de pharmacodynamie et de therapie, Ghent, 1949, 79, pp. 282-289.

HOUGS-OLSEN, W.: Comparative investigations into the analgesic effects of morphine and dl-6-dimethylamino-4, 4-diphenyl-3-heptanone hydrochloride, Acta pharmacologica et toxicologica, Copenhagen, 1949, 5, pp. 33-44.

HOWE, E. E.; SLETZINGER, M.: Resolution of dl-methadon, and dl-isomethadon, Journal of the American Chemical Society, Rochester, New York, 1949, 71, pp. 2935-2936.

I

ISBELL, H.: The addiction liability of some derivatives of meperidine, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 97, pp. 182-189.

ISBELL, H.; EISENMANN, A. J.: Physical dependence liability of drugs of the methadon series and of 6-methyl-dihydromorphine, Federation Proceedings, Baltimore, 1948, 7, p. 162.

ISBELL, H.; VOGEL, V. H.: The addiction liability of methadon (amidone, dolophine, 10820) and its use in the treatment of the morphine abstinence syndrome, American Journal of Psychiatry, Baltimore, 1949, 105, pp. 909-914.

J

JENNEY, E. H.; PFEIFFER, C. C.: Comparative analgesic and toxic effects of the optical isomers of methadon and isomethadon, Federation Proceedings, Baltimore, 1948, 7, p. 231.

K

KIRCHHOF, A. C.; DAVID, N. A.: Clinical experience with methadon (dolophine), Anesthesiology, Philadelphia, 1948, 9, pp. 585-593.

L

LINDER, E.: Polamidon, a new analgesic, Süddeutsche Apotheker-Zeitung, Stuttgart S., 1949, 89, pp. 449-451.

LUCAS, G. H. W.: Color and crystal tests for the identification of methadon and isomethadon, Federation Proceedings, Baltimore, 1949, 8, p. 317.

LUND, C. J.: Newer obstetric analgesics; preliminary evaluation of compounds No. 10720 and No. 10820 (dolophine), American Journal of Obstetrics and Gynecology, St. Louis, Missouri, 1948, 55, pp. 1007-1015.

M

MAY, E. L.; MOSETTIG, E.: Some reactions of isoamidone, Journal of Organic Chemistry, Baltimore, 1948, 13, pp. 665-666..

P

POHLAND, A.; MARSHALL, F. J.; CARNEY, T. P.; Optically active compounds related to methadon, Journal of the American Chemical Society, Rochester, New York, 1949, 71, pp. 460-462.

POWELL, C. E.; CHEN, K. K.: Action of dolophine on the animal uterus, American Journal of Pharmacy, Philadelphia 4, Pennsylvania, 1948, 37, pp. 516-518.

POWERS, B. R.: Use of methadone to combat withdrawal symptoms of dilaudid addiction; case report, Journal of the Tennessee State Medical Association, Nashville, Tennessee, 1949, 42, p. 83.

S

SCHULDINER, J. A.: Identification of amidone, Analytical Chemistry, Washington, D. C., 1949, 21, pp. 298-300.

SPEETER, M. E.;. BYRD, W. M.; CHENEY, L. C.; BINKLEY, S. B.: Analgesic carbinols and esters related to amidone, Journal of the American Chemical Society, Rochester, New York, 1949, 71, pp. 57-60.

STEELE, C. W.: A comparison of the antidiuretic effect of demerol and of methadon diuresis in congestive heart failure; a case report, Journal of the Maine Medical Association, Portland, 1949, 40, pp. 277-281.

T

TAINTER, M. L.: Estudio comparativo de algunas acciones del demerol y del methadon (Comparative study of some aspects of the action of demerol and methadon), Boletin de la Asoc. de medica de Puerto Rico, San Juan, P. R., 1948, 40, pp. 1-14.

TAINTER, M. L.; BUCHANAN, O. H.: A comparison of certain actions of demerol and methadone, California and Western Medicine, San Francisco, 1949, 70, pp. 35-43.

THORP, R. H.: The pharmacology of the optical isomers of amidone (2-dimethyl-amino-4:4-diphenylheptanene-5), British Journal of Pharmacology and Chemotherapy, London, 1949, 4, pp. 98-104.

44 W

WALTON, E.; OFNER, P.; THORP, R. H.: New analgesics. III. Homologs of amidone, isoamidone, and some related compounds, Journal of the Chemical Society, London, 1949, pp. 648-655.

WATSON, R. C.; BOWMAN, M. I.: Microchemical identification of amidone, Journal of the American Pharmaceutical Association, Washington, D. C., 1949, 38, pp. 369-373.

WATTS, D. T.: Isomers of methadon and isomethadon and respiration of brain homogenates, Federation Proceedings, Baltimore, 1949, 8, p. 343.

WATTS, D. T.: Inhibition of succinic oxidase system by meperidine, methadon, morphine and codeine, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 95, pp. 117-121.

WAY, E. L.; SUNG, C. Y.; McKEL-WAY, W. P.: The absorption, distribution and excretion of d,l-methadone, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 97, pp. 222-228.

WAY, E. L.; SUNG, C. Y.; McKELL-WAY, W. P.: Fate of dl-methadon, Federation Proceedings, Baltimore, 1949, 8, pp. 344-345.

WILSON, W.: Tetrahydrofurans related to amidone, Journal of the Chemical Society, London, 1948, pp. 1993-1994.

WOLFF, P. O.: On pethidine and methadone derivatives, Bulletin of the World Health Organization, Geneva, 1949, 2, pp. 193-204.

D. OTHER SYNTHETIC DRUGS

D

DAENICK, L.; LIBBRECHT, L.: Sur l'action centrale de l'ester diethylamino ethylique de l'acide phenyl cyclopentane carboxylique (Parpanit), Archives lnternationales de Pharmacodynamie et de Therapie, Ghent, vol. LXXIX, fasc. 11-111, pp. 263-268.

DESOILLE, H.; COLIN; FELDSTEIN: Intolerance a l’egard de l'eubine, Archives de maladies professionales, de medecine du travail et de securite sociale, Paris, 1949, 8, pp. 281-282.

G

GEILL, T.: Nyere laegemidler; entalgin (New remedies: entalgine), Mskr. prakt. laegegern., Copenhagen, 1949, 27, p. 437.

GOODSON, L. H.; MOFFETT, R. B.: Analgesics. III. Hydrochloridea of phenylalkylamines, Journal of the American Chemical Society, Rochester, New York, 1949, p. 71.

H

HAPKE, F. B.; BARNES, A. C.: The obstetric use and effect on fœtal respiration of nisentil, American Journal of Obstetrics and Gynecology, St. Louis, 1949, 58, p. 799.

J

JERSILD, M.: Butalgin sore smertestil-lende middel (Butalgin an analgesic), Uges-krift for laeger, Copenhagen, 1949, 111, p. 425.

K

KAAE, S.: Butalgin, et nyt Analgeticum (Butalgin, a new analgesic), Nordisk medicin, Stockholm, 1948, 38, pp. 684-687.

L

LEWIS, J. R.: Action of 1-methyl-4-(3-hydroxyphenyl)-4-piperidyl ethyl ketone on the gastrointestinal tract, Proceedings of the Society for Experimental Biology and Medicine, New York, 1949, 71, pp. 300-303.

M

MAGALDI, J. B.; BRANDAO, J. A.: Acao analgesica do 6-dimetilamino 4,4-difenil 3-heptanona (Analgesic action of 6-dimetilamino 4,4-difenil 3-heptanone), Hospital, Rio de Janeiro, 1949, 35, pp. 543-548.

O

OFNER, P.; THORP, R. H.; WALTON, E.: A new analgesic drug analogous to isoamidone, Nature, London, 1949, 163, p. 479.

Part VI DRUG ADDICTION

A

ANONYMOUS (Correspondence): Narcotic poisoning cases, Journal of the American Medical Association, Chicago, 1949, 141, p. 861.

ANSLINGER, H. J.: Methadon addiction (Correspondence), Journal of the American Medical Association, Chicago, 1948, 138, p. 609.

B

BOOY, J.: Arts en morphinegevaar (Medicine and the danger of morphine), Nederlandsch tijdscrift voor geneeskunde Haarlem, Holland, 1949, 93, pp. 2571-2576.

BREAUX, R. P.: Dental care for narcotic addicts in the U.S. Public Health Service Hospital, Lexington, Kentucky, Military Surgeon, Washington D. C., 1949, 105, pp. 209-211.

D

DESOILLE, H.; COLIN; FELDSTEIN: Intolerance a l’egard de l'eubine, Archives des maladies professionnelles, de medecine du travail et de securite sociale, Paris, 1949, 8, pp. 281-282.

E

EPHRATI, P.: (Treatment of intoxication by morphine and other hypnotics by intravenal injection of nikethamide),* Harefuah, Tel Aviv, 1949, 37, p. 6.

EUSTACE, H. J.: Addiction under the Mental Treatment Act, Eire, 1945, Journal of Mental Science, London, 1949, 95, No. 100, pp. 693-695.

F

FARAGO, I.: Zur Frage der Entstehung von Suchtkrankhaeiten (The origin of addiction diseases), Monatsschrift fur Psychiatrie und Neurologie, Basel, 1949, 117/2, pp. 98-115.

H

HEUBNER, W.: Genuss und Betaubung durch chemische Mittel (Pleasure and addiction through chemical means), Berlin, Akad-Verlag, 1948, 38, 38 pp.

HILLEMAND, P.; BARRE, y.; LE-COEUR: Toxicomanie et metabolisme basal, Bulletins et memoires de la Societe medicale des hopitaux de Paris, Paris, 1949, 65, pp. 173-176.

HILLEMAND, P.; LECOEUR: La megasplanchnie digestive chez les toxicomanes, Bulletins et memoires de la Societe medicale des hopitaux de Paris, Paris, 1949, 65, pp. 143-150.

It has not been possible to obtain the original title of this-article.

I

ISBELL, H.; EISENMAN, A. J.: The addiction liability of some drugs of the methadon series, The Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1948, 93, pp. 305-313.

ISBELL, H.; WILKER, A.; et al: Liability of addiction to 6-dimethylamino-4-4-diphenyl-3-heptanone (methadon, amidone or 10820) in man; experimental addiction to methadon, Archives of Internal Medicine, Chicago, 1948, 82, pp. 362-392.

L

LEWIS, J. R.: A study of the development of tolerance to the actions of l-methyl-4-(3 hydroxy-phenyl) 4-piperidyl ethyl Ketone hydrochloride in dogs, Journal of Pharmacology and Experimental Therapeutics, Baltimore, 1949, 96, pp. 410-415.

LUTTGENS, W. F.: Endocarditis in main line opium addicts; report on 11 cases, Archives of Internal Medicine, Chicago, 1949, 83, pp. 653-654.

M

MALZBERG, B.: A statistical study of psychoses due to drugs or other exogenous poisons, American Journal of Psychiatry, Baltimore, 1949, 106, pp. 99-106.

O

ORTH, O. S.: Liabilities in the use of morphine, Wisconsin Medical Journal, Madison, Wisconsin, 1949, 48, p. 743.

P

PHATAK, N. M.; MACONEY, J.; DAVID, N.: Use of hyperglycerine response for estimating addiction potentialities of analgesic compounds, Federation Proceedings, Baltimore, 1948, 7, p. 249.

POWERS, B. R.: Use of methadon to combat withdrawal symptoms of dilaudid addiction; case report, Journal of Tennessee State Medical Association, Nashville, Tennessee, 1949, 42, p. 83.

S

SOLIS, J.: Un caso de dolantinismo (A case of addiction to dolantin), Revista clinica espanola, July 15, 1946, 22, pp. 48-50.

W

WALKER, C.: Dangerous symptoms after injections of heroin (diamorphine), British Medical Journal, London, 1949, 1, p. 619.

WIEDER, H.: Objective evaluation of insulin therapy of the morphine abstinence syndrome, Journal of Nervous and Mental Diseases, Richmond, Virginia, 1949, 110,pp. 26-35.

WIKLER, A.: Reactions of chronic decorticated dogs during a cycle of addiction to methadon, Federation Proceedings, Baltimore, 1948, 7, p. 265

Part VII MISCELLANEOUS WORKS

A

AMMITZBOLL, F.: Lucamid, et nyt analgeticum (Lucamid, a new analgetic), Nor-disk medicin, Stockholm, 1949, 41, p. 376.

S

SALOMON, Kurt; GABIRO, Beverly Wescott; THALE, Thomas: A study of mescaline in human subjects, Journal of Pharmacology and Experimental Therapeutics, Baltimore 2, 1949, 95, pp. 455-459.

SANTAVY, F.: (Polarography of berberine, hydrastine and cotarnine),* Collection of Czechoslovak Chemical Communications, Prague and New York, 1949, 14, pp. 377-387.

SCHULDINER, U. A.: Color reactions for copalquin bark extract, Journal of the American Pharmaceutical Association, Washington, D. C., 1949, 38, pp. 292-293.