Up to September 2014, a total of 388 new psychoactive substances (NPS) were reported to the UNODC Early Warning Advisory (EWA) through data submissions from Member States and national drug testing laboratories participating in the International Collaborative Exercises (ICE) programme. Since December 2013, an increase of 11% in the total number of NPS reported to EWA has be noted. Most countries and territories reported ketamine & related phencyclidine-type substances (61 countries), followed by synthetic cannabinoids (60 countries) and phenethylamines (57 countries).

Since the beginning of the year, synthetic cannabinoids continue to account for the majority of NPS reported (39%) followed by synthetic cathinones (18%) and phenethylamines (15%). Out of all reported substances in 2014, 25 synthetic cannabinoids, 7 synthetic cathinones and one phenethylamine were reported to UNODC EWA for the very first time together with 7 NPS from other chemical substance classes.