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August 2015 - UNODC EWA: Fifteen novel synthetic cannabinoids reported to UNODC EWA since the beginning of the year

From the beginning of the year, 50 new substances were reported to the UNODC EWA for the first time by direct submissions of laboratories, data sharing agreements with international and regional organisations* and by laboratories participating in the International Collaborative Exercises (ICE) programme. Of these newly reported substances, 15 were novel synthetic cannabinoids, 13 of which contain the amide linking group, first seen in APINACA reported to the UNODC EWA in 2012.

Novel synthetic cannabinoids in 2015 (further chemical information available for registered users at NPS Chemical Information):

1.  5F-AB-FUPPYCA, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-5-(4-fluorophenyl)-1H-pyrazole-3-carboxamide
2.  5F-ADB-PINACA, N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide
3.  5F-EMB-PINACA, Ethyl 2-[[1-(5-fluoropentyl)indazole-3-carbonyl]amino]-3-methyl-butanoate
4.  5F-PY-PICA, (1-(5-fluoropentyl)-1H-indol-3-yl)(pyrrolidin-1-yl)methanone
5.  5F-PY-PINACA, (1-(5-fluoropentyl)-1H-indazol-3-yl)(pyrrolidin-1-yl)methanone
6.  AB-PINACA N-(2-fluoropentyl), N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(2-fluoropentyl)-1H-indazole-3-carboxamide
7.  Adamantyl-THPINACA, N-(adamantan-1-yl)-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-indazole-3-carboxamide
8.  AMB-CHMINACA, methyl (1-(cyclohexylmethyl)-1H-indazole-3-carbonyl)-valinate
9.  APP-CHMINACA, N-(1-amino-1-oxo-3-phenylpropan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide
10. CUMYL-5F-P7AICA, 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide
11. EMB-FUBINACA, ethyl (1-(4-fluorobenzyl)-1H-indazole-3-carbonyl)valinate
12. FUB-JWH-018, (1-(4-fluorobenzyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone
13. MDMB-FUBICA, Methyl 2-(1-(4-fluorobenzyl)-1H-indol-3-carboxamido)-3,3-dimethylbutanoate
14. 5F-MDMB-PINACA, methyl 2-(1-(5-fluoropentyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate
15. SDB-005, naphthalen-1-yl 1-pentyl-1H-indazole-3-carboxylate


*)’New psychoactive substances notified to the EU Early Warning System in the first half of 2015 under the terms of Council Decision 2005/387/JHA, European Union Early Warning System, European Monitoring Centre for Drugs and Drug Addiction (EMCDDA)’

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