VIENNA, Austria – 6 December 2025: The decisions adopted by the Commission on Narcotic Drugs (CND) during its 68th regular session from 10 to 14 March 2025 to add hexahydrocannabinol (HHC) to Schedule II and carisoprodol to Schedule IV of the Convention on Psychotropic Substances of 1971, entered into force on 6 December 2025.

Hexahydrocannabinol (HHC) is the first semi-synthetic cannabinoid that has been placed under international control. The substance first emerged in 2022, when it was reported by 23 countries and territories across Europe. Subsequently, HHC has been reported by 56 countries and territories in all continents to date. So far, 22 synthetic cannabinoids have been scheduled since 2015 (see Dashboard Public, or for more comprehensive data visualizations Dashboard Pro - if not registered please sign up here).

For further information please see:

World Health Organization, “47th Expert Committee on Drug Dependence documents – Critical reviews”. Available at: https://who.int/groups/ecdd/forty-seventh-ecdd-documents (accessed on 1 December 2025).

UNODC, "March 2025 – UNODC: Five NPS and one medicine "scheduled" at the 68th Session of the Commission on Narcotic Drugs", news clip, 12 March 2025.

UNODC, "November 2024 - UNODC EWA: New evolution of “semi-synthetic” cannabinoids", news clip, November 2024.

UNODC, "January 2025 - WHO: World Health Organization recommends five NPS and one medicine for scheduling", news clip, 24 January 2025.