VIENNA, Austria – 12 March 2026: At its 69th regular session, held from 9 to 13 March 2026, the Commission on Narcotic Drugs (CND) decided to place three new psychoactive substances (NPS) under international control. Following recommendations by the World Health Organization, two nitazenes were added to the Schedule I of the Single Convention on Narcotic Drugs of 1961 as amended by the 1972 Protocol and one synthetic cannabinoid receptor agonist to Schedule II of the Convention on Psychotropic Substances of 1971. UNODC EWA will communicate the date of when the scheduling decisions enter into force via a follow up early warning advisory.

Added to the Single Convention on Narcotic Drugs of 1961, as amended by the 1972 Protocol – (Schedule I):

1. N-Pyrrolidino isotonitazene (Isotonitazepyne)

2. N-Desethyl etonitazene

Added to the Convention on Psychotropic Substances of 1971 – (Schedule II):

3. MDMB-FUBINACA

The UNODC Early Warning Advisory (EWA) on NPS regularly provides scientific information to Member States and the World Health Organization for the identification of the most harmful, prevalent, and persistent NPS in support of review processes for national and international control. To date, UNODC EWA has recorded 1444 unique NPS, showcasing the need for ongoing vigilance. Stay informed on emerging trends through UNDOC EWA visualisations and news.

For further information please see:

United Nations Office on Drugs and Crime (UNODC), “January 2026 – WHO: World Health Organization recommends three NPS for scheduling”, news clip, 27 January 2026.

United Nations Office on Drugs and Crime (UNODC), “February 2026 - Increasing nitazene and orphine analogues (synthetic opioids) and the implications for the use of test strips”, news clip, 25 February 2026.

United Nations Commission on Narcotic Drugs, Sixty-ninth session, 9-13 March 2026.