This presentation was recorded on 4 June 2026 for the Australian Prompt Response Network (PRN) national meeting held on 16 June 2026. It provides a brief overview of the emergence of orphines, including their chemical characteristics, pharmacological profile, patterns of use, and increasing presence in illicit drug markets. The presentation also highlights challenges related to detection, surveillance, and early warning systems, as well as associated public health risks and implications for forensic and policy responses.

Disclaimer:

This recording was conducted in English. YouTube offers auto‑dubbed audio tracks in multiple languages to improve accessibility; however, accuracy may vary, particularly for chemical and substance names. English and other languages automatically generated subtitles are also available to support understanding alongside this feature.

References:

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9. News: July 2025 – China: Announcement of class scheduling of “nitazene” analogues.
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13. News: May 2026 – The emerging threat of cychlorphine: A new synthetic opioid raising concerns globally for public health.
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17. UNODC Early Warning Advisory Tox-Portal.
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19. Health Canada. (2026). News Release: Government of Canada takes quick action to disrupt illegal drug production.