Bibliography

Sections

INTRODUCTION
PART I
PART II

Details

Pages: 42 to 51
Creation Date: 1952/01/01

Bibliography

SCIENTIFIC PUBLICATIONS ON NARCOTIC DRUGS FOR 1951

INTRODUCTION

The following bibliography has been prepared by the Secretariat and includes scientific publications on narcotic drugs which appeared during 1951, as well as a few which appeared earlier but could not, for various technical reasons, be included in the preceding lists, published in No. 3 of Volumes II and III of the Bulletin on Narcotics. This bibliography has no claim to be complete, and information regarding books or articles not included in it would be gratefully received by the Division of Narcotic Drugs, Department of Social Affairs, United Nations Secretariat.

The bibliography has been arranged by subject in the following way:

Part I. General and reference works

Part II. Opium poppy, opium and drugs manufactured therefrom

  1. Morphine

  2. Opium poppy and opium

  3. Other phenanthrene alkaloids and derivatives of opium (under the Conventions)

  4. Other drugs and substances derived from the opium poppy

Part III.

  1. A. The coca leaf

  2. B. Drugs manufactured from the coca leaf

Part IV. Cannabis and its derivatives

Part V. Synthetic drugs

  1. General works

  2. Pethidine and related compounds

  3. Methadone and related compounds

  4. Morphinan and morphine synthesis

  5. Other synthetic analgesics

Part VI. Addiction to narcotic drugs

Part VII. Miscellaneous

Under each heading, publications are arranged alphabetically by author. Due to the nature of the sources available to the Secretariat for preparing this bibliography, several of the titles are given in translation only. They are preceded by an asterisk.

PART I

GENERAL AND REFERENCE WORKS

ABREU, B. E.; ELLIOTT, H. W.; SUTHERLAND, V. C.; MARGOLIS, L.; LIDDLE, G. W.; SIMON, A.: Cerebral metabolic and circulatory effects of analgetics in man. Journal of Pharmacology and Experimental Therapeutics, 1950, 98:1.

ALDOUS, J. D.; WHILLIANS, M G: A new method for measuring the analgesic power of drugs in human subjects. Proceedings of the Nova Scotian Institute of Science, 1950, 22:3, p. 42.

ANONYMOUS: Réglementation des substances vénéneuses, Avenir médical, 1951, 48:2, pp. 35-37.

ANSLINGER, H. J.: Control of the traffic in narcotic drugs. Merck Report, 1951, 60:4, pp. 33-38.

ARBUSOV, S: Antagonism i sinergizm mezhdu narkotikami i simpatomimeticheskimi aminami v destvii na tsentral' nervnuiu sistemu teplokrovnykh zhivotnykh (Antagonism and synergism between narcotics and sympatomimetic amines in action upon the central nervous system in warm blooded animals). Fisiologicheskoi Zhurnal SSSR, 1950, 36 6, pp. 704-711.

BANDELIN, F J.: The colorimetric determination of various alkaloids Journal of the .American Pharmacological Association, 1950, 39:9, pp. 493-495.

BEECHER, Henry K.: Study of analgesics. Bulletin on Narcotics, 1951, 3:4, pp. 9-15.

BONNYCASTLE, D. D; IPSEN, J A study of the qualitative differences in response to analgetic drugs Acta Pharmacoloqica et Toxicologiqua, 1950, 6 4, pp. 333-353.

BBAMFORD, Frank: Poisons. Their Isolation and Identification Philadelphia. Blakiston Co, 1951, 316 pp.

BUCHEL, L.; MCILWAIN, H : Narcotics and the inorganic and creatine phosphates of mammalian brain British Journal of Pharmacology and Chemotherapy, 1950, 5:4, pp. 465-473.

CARLESS, J. E.; WOODHEAD, H. B.: Separation of alkaloids by paper chromatography. Nature, 1951, 168:4266, p. 203.

CARRATALA, Rogielo: Le délit dans la fabrication et la vente des drogues qui produisent (la) toxicomanie. Annales de médecine légale et de criminologie, 1951, 31:4, pp. 131-137.

CHEN, J. Y. P.; BECKMAN, H.: A satisfactory apparatus for study of analgesia in mice. Science, 1951, 113.2944, p. 631.

COHEN, E. N.; BEECHER, H. K: Needless use of a narcotic in preanesthetic medication. Federation Proceedings, 1951, 10:1, p. 288.

COOK, L.: BONNYCASTLE, D. D.: Action of common analgetic materials on spinal reflexes. Federation Proceedings, 1951, 10:1, p. 289.

DRIESEN, W.; HAHN, F.; RUMMEL, W.: Elektrencephalographische Analyse der Wechselwirkung von Narkotikum und Analeptikum (Electroencephalographic analysis of the reciprocal action of narcotics and analeptics). Archiv für experimentelle Pathologie und Pharmakologie, 1951, 212:3, pp. 243-250.

DUFRESNE, R. R.: A propos des narcotiques. Union médicale du Canada, 1951, 80:7, pp. 843-845.

FICHTENBERG, D. G.; LEVY, J.: Sur la réalisation expérimentale de l'état d'accoutumance. Thérapie, 1950, 5:6, p. 277

GREEN, A. F.; YOUNG, P. A.; GODFREY, E. I.: Comparison of heat and pressure analgesiometric methods in rats. British Journal of Pharmacology, 1951, pp. 6572-6587.

GUTNER, L. B.; GOULD, W. J.; BATTERMAN, R. C.: Effects of potent analgesics upon vestibular functions. Federation Proceedings, 1951, 10:1, p. 304.

HAAS, H. : Vergleichende Untersuchungen mit Analgetika (Comparative studies on analgesics). Archiv für experimentelle Pathologie und Pharmakologie, 1950, 212:1-2, pp. 162-163.

HERR, F.; PÓRSZÁSZ: Eine neue Methode zur Untersuchung der schmerzstillenden Wirkung (A new method for the testing of analgetic effect). Archiv für experimentelle Pathologie, 1950, 210 3, pp. 289-293.

HOFMANN, H.; HELD, U.: (Side actions of analgesics). Pharmazie, 1951, 6, pp. 316-321.

HOUDE, R. W.; WIKLER, A.; IRWIN, S: Comparative actions of analgesics, hypnotic and paralytic agents on hindlimb reflexes in chronic spinal dogs. Journal of Pharmacology and Experimental Therapeutics, 1951, 103, pp. 243-248

HUGGINS, R. A.; GLASS, W. G; BRYAN, A R.: The cardiovascular effects of some narcotics. Archives internationales de Pharmacodynamie, 1950, 86, pp. 112-120.

JUNKCRMAN, C L; HEEN, R. C; POHLE, H. W: Clinical experience with a new analgesic agent. Lancet, 1951, 71:7, pp. 263-265.

KEENAN, G. L : Microscopy of some important alkaloids. IV. Chemist-Analyst. 1951, 40, pp. 4-9, 11, 14.

KELLY, G.: Medico-moral notes. Linacres Quarterly, 1950, 17:4, pp. 3-17.

KERHAW, J.; BOUQUET, A.: Plantes médicinales et toxiques de la Côte-d'Ivoire-Haute-Volta Paris, Vigot, 1950, 300 pp.

KIMURA, K. K.; DEBOER, B.; WALTS, L.; KEITH, E: Experimental tolerance to hyperglycemia produced in rabbits by analgesic compounds. Federation Proceedings, 1951, 10:1, p. 314.

KÖNIG, F. E : Der Einfluss der einzelnen Anasthetica, Analgetica, und Hypnotica auf das Kind (Effect of anesthetics, analgesics, and hypnotics on the child). Gynaecologia, 1951, 131:5, pp. 298-316.

LA BELLE, A.; TISLOW, R.: A method of evaluating analgesics of the antiarthralgic type in the laboratory animal. Journal of Pharmacology and Experimental Therapeutics, 1950, 98:1, p. 19.

LENDLE, L.: Pharmakologie der Rauschgifte und Betaubungsmittel (Pharmacology of narcotic poisoning and narcotics). Oeffentliche Gesundheitsdienst, 1950, 12:5, pp. 372-386.

LONJUMEAU, LEVEQUE: Les intolérances aux opiacés et la vitamine B-1. Bulletin de l'Académie nationale de médecine, 1951, 135:3-4, pp. 45-48.

LUCKNER, H.; MAGUN, R.: Eine Methode zur quantitativen Prufung analgetischer Wirkungen im Tierversuch (A method of quantitative testing of analgesic effects in animal study). Zeitschrift fur die gesamte experimentelle Medizin, 1951, 117:2, pp. 133-145.

MACCIO, Isidro: (Paper chromatography applied to the study of alkaloidcontaining extracts). Revista Farmacéutica, Buenos Aires, 1950, 92, pp. 107-108.

MCLENNAN, H.; ELLIOTT, K. A. C.: Effects of convulsants and narcotic drugs on acetylcholine synthesis. Journal of Pharmacology and Experimental Therapeutics, 1951, 103, pp. 35-43.

MARION, D, GAGNON, J. N.: Analgésie et anesthésie en obstétrique Union médicale du Canada, 1951, 80 ·7, pp. 843-845.

MESNARD, P.; BOUSSEMART, E.: Séparation par chromatographie de partage sur papier des constituants alcaloidiques d'un soluté injectable Bulletin des travaux de la Société de pharmacie de Bordeaux, 1951, 88, pp. 175-177.

MÜLLER, K.: Rauschgifte und Genussmittel (Narcotic and pleasure drugs). Basle, Benno Schwabe, 1951, 431 pp

MUNIER, Roger; MACHEBOEUF, Michael: Essais préliminaires de microchromatographie sur papier de divers alcaloides par des phases miscibles à l'eau (Preliminary experiments on paper chromatography of various alkaloids with the use of liquid phases miscible with water). Bulletin de la Société de chimie biologique, 1950, 32, pp. 904-907.

PLEAT, G. B.; HARLEY, J. H; WILBERLEY, S. E.; Use of infra-red spectra in the qualitative and quantitative determination of alkaloids Journal of the American Pharmaceutical Association, 1951, 40: 1, pp. 107-110.

RAO, N. Prabhakara: Active principles of certain important medicinal and insecticidal plants. Antiseptic, 1950, 47, pp. 885-989.

RIMATTEI, F.; OTTO, E.: (Potentiometric determination of alkaloids). Tunisie médicale, 1951, 39, pp. 886-891.

ROSENBERG, A. J.; ETLING, N.: Action des narcotiques sur l'acétylcholine libre et live du cerveau de rat. C. R. des séances de la Société de biologie, 1951, 145:7-8, pp. 527-528.

SAUNDERS, L.; SRIVASTAVA, R. S.: Potentiometric titration of alkaloidal salts. Journal of Pharmacy and Pharmacology, 1951, 3, pp. 78-85.

SCHOETENSACK, W.; HANN, J.: Zum Angriffpunkt von Narkotika (The point of attack of narcotic substances). Archiv für experimentelle Pathologie und Pharmakologie, 1950, 212:1-2, pp. 159-160.

SLOMKA, M. B.; SCHUELER, F. W.: Chemical constitution and analgetic action. Federation Proceedings, 1950, 9.1, p. 316. Journal of the American Pharmaceutical Association, 1951, 40:1, pp. 47-51.

TUOHY, E B: Obstetrical anesthesia and analgesia. Southern Medicine and Surgery, 1951, 113·1, pp. 1-5.

TULLAR, P. E.: Measurement of analgesia in rats. Federation Proceedings, 1951, 10:1, pp. 341-342.

VAILLE, C.; STERN, G.: Contribution à l'étude des toxicomanies. II. - Quelques aspects du trafic illicite des stupéfiants. Annales pharmaceutiques françaises, 1950, 8:9-10, pp 95-100.

WEBB, J. L.; KAC, Elliott: Effects of narcotics and convulsants on tissue glycolysis and respiration Journal of Pharmacology and Experimental Therapeutics, 1951, 103:1, pp. 24-34.

PART II

OPIUM POPPY, OPIUM AND DRUGS MANUFACTURED THEREFROM

A. OPIUM POPPY AND OPIUM

AKÇASU, Allaeddin: Turkiyede yetisen afyonlarin billur sekilleri (Forms of crystals of opium grown in Turkey). Tip Fakültesi Mecmuasi (Bull. Faculté médecine d'I stanbul), 1950, 13, pp. 287-300, English summary: pp. 301-304.

AKÇASU, A: The forms of crystals in Turkish opium. United Nations document ST/SOA/SER.K/2, 1951.

ANONYMOUS: Forsøg med Sorter of Opiat-Valmue (Variety trial with opium poppy in the years 1944-1947). Tidskrift for Planteavl, 1949, 52:4, pp. 713-714.

BAERHEIM SVENDSEN, A.: Papierchromatographie und quantitative Bestimmung des Morphins im Opium. III. über Papierchromatographie in der phytochemischen Analyse (Paperchromatography and quantitative determination of morphine in opium; paperchromato- graphy in phytochemical analysis). Pharmaceutica Acta Helvetiae, 1951, 26:8, pp. 323-333.

BARBIER, A.: The extraction of opium alkaloids. Bulletin on Narcotics, United Nations, 1950, 2:3, pp. 22-29.

BERSILLON, G.: Sur le point végétatif de Papaver somniferum L.; structure et fonctionnement. C. R. Académie des sciences, Paris, 1951, 232:26, pp. 2470-2472.

KNAFFL-LENZ, Erich: The determination of morphine in raw opium, United Nations document ST/SOA/SER.K/3, 1951.

NICHOLLS, J. R.; KELLETT, E.G.: The Ratio of Narcotine to Meconic acid in Relation to the Origin of Opium; ST/SOA/SER.K/5, 1951. The determination of Narcotine and Meconic acid in Opium; ST/SOA/SER.K/6, 1951 The determination of Narcotine and Meconic Acid in

Opium; ST/SOA/SER.K/7, 1951. 24 September 1951 (United Nations documents).

TOMKO, Josef: (Opium alkaloids in Slovak poppies). Chemicke Zvesti, 1950, 4, pp. 475-478.

UNITED NATIONS SECRETARIAT: Culture of opium poppy in Turkey. Bulletin on Narcotics, United Nations, 1950, 2:1, pp. 15-27.

UNITED NATIONS SECRETARIAT: The determination of morphine in opium by extraction: A new method. Document ST/SOA/SER.K/1, 1951.

WALTER, C.: L'intérêt d'un véhicule retardé dans la médication opiacée. Journal des praticiens, Paris, 1951, 65:33, pp. 396-397.

B. MORPHINE

CASTAGNOU, R.; PAOLETTI, C.: Sur une nouvelle réaction colorée de la morphine. Bulletin de la Société de pharmacie de Bordeaux, 1951, 89, pp. 91-92.

COHEN, Ellis N.; BEECHER, Henry K.: Narcotics in preanesthetic medication. Journal of the American Medical Association, 1951, 147, pp. 1664-1668.

DIEZ, E. D.: Anestesia endovenosa con la mezcla morfina-escopolamina (Endovenous anesthesia with morphine-scopolamine). Revista de la Asociación Médica Argentina, 1950, 64: 683-684, pp. 364-366.

DUKE, H. N.; PICKFORD, M.; WATT, J. A.: The antidiuretic action of morphine: its site and mode of action in the hypothalamus of the dog. Quarterly Journal of Experimental Physiology and Cognate Sciences, 1951, 36:3, pp. 149-158.

DUMAZER, R; LAMY, R.: Niche en plateau de la petite courbure de l'antre gastrique; intérêt de la pharmaco-radiographie morphinique. Journal de radiologie et d'électrologie, 1950, 31:7-8, p. 505.

EISENMAN, A. J.: Effect of addiction to morphine on excretion of water and electrolytes. Federation Proceedings, 1951, 10:1, p. 180.

FICHTENBERG, Denise G.: Sort de la morphine chez le rat accoutumé. Thérapie. 1950, 5:6, pp. 277-278.

FICHTENBERG, Denise G.: Study of experimental habituation to morphine.

Bulletin on Narcotics, United Nations, 1951, 3:3, pp. 19-42; 4, pp. 16-52.

FOSTER, G. E.; MACDONALD, J.; WHITTET, T. D.: The stability of injection of morphine sulfate. Journal of Pharmacy and Pharmacology, 1950, 2:10, pp. 673-684.

FROMMEL, E.; VALETTE, F.: De la potentialisation de l'effet analgésique de la morphine de la dihydromorphinone par le salicylate d'ésérine. Archives des sciences, 1951, 4:2, pp. 128-129.

GARCIO-BLANCO, J.; VINA, J.; ANTON, V.: Variaciones que el coma insulínico imprime a la acción de la codeína y morfina sobre la presión arterial (Variations produced by insulin coma in the effect of codeine and morphine on arterial pressure). Revista Española de Fisiologia, 1950, 6:3, pp. 177-180.

GASTALDI, E.: Preparazione di cloridrito di morfina in cubi leggerissimi (Preparations of morphine hydrochloride in very light cubes). Bollettino chimicofarmaceutico, 1951, 90:7, pp. 297-298.

GLEIZE-RAMBAL, L.: Lésions de la petite courbure mises en évidence seulement après morphinisation. Journal de radiologie et d'électrologie, 1950, 31.7-8, p. 514.

HILL, H. E.; KORNETSKY, C. H.; FLANARY, H. G.; WIKLER, A.: Effects of anxiety and morphine on discrimination of painful stimuli. Federation Proceedings, 1951, 10:1, p. 309.

HOUDE, R. W.; WIKLER, A.: Delineation of the skin-twitch response in dogs and the effects thereon of morphine, thiopental and mephenesin. Journal of Pharmacology and Experimental Therapeutics, 1951, 103, pp. 236-242

IRWIN, S.; HOUDE, R. W.; BENNETT, D. R.; HENDERSHOT, L. C.; SEEVERS, M. H.: The effects of morphine, methadone and meperidine on some reflex responses of spinal animals to nociceptive stimulation Journal of Pharmacology and Experimental Therapeutics, 1951, 101:2, pp. 132-143.

KALVODA, R; ZYKA, J.: (Use of polarometric titrations to determine small quantities of morphine). Casopis Ceskeho Lekárnictva, 1949, 62, pp. 134-140.

KELLY, P. A: Methods for prolonging the action of morphine. American Journal of Pharmacy, 1951, 123:8, pp. 254-259.

KELLY, P. A.: Methods for prolonging the analgesic action of morphine. Australasian Journal of Pharmacy, 1951, 31:379A, pp. 816-820.

KELEMEN, E; PATAKY, S. J.: Reaction de la morphine et du sérum sanguin. Acta Medica Academiae Scientiarum Hungaricae, 1951, 2:2, pp. 319-323.

KNOLL, J; KOMLOS, E: Die analgetische Wirkung des Atropins und sein Synergismus mit Morphin und Prostigmin (The analgesic effect of atropine and its synergism with morphine and prostigmine). Acta Physiologica Acade-

miae Scientiarum Hungaricae, 1951, 2, pp. 57-69.

KOMLOS, E.; PÓRSZÁSZ, J.; KNOLL, J: Morphin-prostigmin synergismus (Morphin-prostigmin synergism). Acta physiologica Hungaricae, 1950, 1:1, pp. 77-90.

KUHN, R. A.; BROMILEY, R B.: Human pain thresholds determined by the radiant heat technique and the effect upon them of acetylsalicylic acid, morphine sulfate and sodium phenobarbital. Journal of Pharmacology and Experimental Therapeutics, 1951, 101:1, pp. 47-55.

LE BRUN, S.; LODDI, L.; PANDOLFINI, A.: Ricerche sul meccanismo del deflusso biliare. I. Sull'azione di alcuni farmaci (morfina, prostigmina, atropina) sul sistema biliare extraepatico (Research on the mechanism of bile flow. I. Effect of various drugs (morphine, prostigmine and atropine) on the extrahepatic biliary tract). Annali Italiani di Chirurgia, 1951, 28:6, pp. 325-348.

MCCRUM, W. R.; INGRAM, W. R.: The effect of morphine on cats with hypothalamic lesions. Journal of Neuropathology and Experimental Neurology, 1951, 10:2, pp. 190-203.

MERCIER, J.: Influence exercée sur la crise audiogene du rat albinos par quelques alcaloides naturels ou synthétiques dérivés de l'opium; morphine, dihydro-oxycodéinone, papavérine. Journal de physiologie, 1950, 42:3, pp. 683-686.

NEDZEL, A. J.: Toxicity of morphine sulfate in white mice under the influence of cold. Journal of Aviation Medicine, 1951, 22:3, pp. 244-247.

OETTEL, H.: über die Morphinausscheidung von Opiumrauchern und Norma- len (Morphine excretion in opium smokers and normal subjects). Archiv für Experimentelle Pathologie und Pharmakologie (Naunyn-Schmiedeberg's), 1950, 212:1-2, pp 163-166.

OPLATKA, Gyorgy; SANDORNE, Szoke: (Extraction of morphine in diffusion batteries like those of sugar mills). Cukoripas, 1950, 3, pp. 56-59.

RUBIN, A.; WINSTON, J.: The role of the vestibular apparatus in the production of nausea and vomiting following the administration of morphine to man. Clinical and experimental data including the effects of dramamine and benzedrine. Journal of Clinical Investigation, 1950, 29:10, pp. 1261-1266.

SEIFERT, P.: Zur Frage des Morphinnachweises mit der Pupillenreaktion der weissen Maus (Morphine determination by means of pupil reaction in the white mouse). Münchener Medizinische Wochenschrift, 1951, 93:1, pp. 182-183.

SIGG, K.: Die therapeutische Anésthesie mit Panthesin. Asthma, Angina pectoris, Herzarrhythmien, Polyarthritis, usw. (Therapeutic anesthesia with Panthesin. Asthma, angina pectoris, cardiac arrhythmias, polyarthritis, etc.). Schweizcrische Medizinisch Wochenschrift, 1951, 81:1, pp. 10-16.

STEPHENS, R. L.: Coloric determination of morphine and diamorphine. Journal of Pharmacy and Pharmacology, 1951, 3, pp. 815-822.

SZENTGYORGYI, D.; BEKES, M.: Die Wirkung des Luminals und Morphinscopolamins auf die Wasserdiurese der Ratten (Effect of luminal and of morphine-scopolamine on diuresis in the rat). Acta Physiologica Academiae Scientiarum Hungaricae, 1951, 2:2, pp. 175-177.

TAKITA, S.: Does the amount of epinephrine in the peripheral blood after morphine injection exceed the limits determinable by the frog legs vessels method. Tohoku Journal of Experimental Medicine, 1950, 52:3-4, pp. 335-340.

TRUCHAUD, M.: Etude de la durée d'action analgésique du pectinate de morphine et du pectinate de dihydrooxycodéinone. Anesthésie et Analgésie, 1951, 8:1, pp. 59-65.

VAN DEN HEUVEL, G.; HEYMANS, J. F.: Mécanisme de l'action hyperglycémiante de l'acétylcholine de la morphine et de la nicotine. Archives internationales de pharmacodynamie et de thérapie, 1950, 83:3, pp. 386-416.

VAUGHAN WILLIAMS, E. M.; STREETEN, D. H. P.: The mode of action of morphine upon the intestine. British Journal of Pharmacology, 1951, 6:2, pp. 263-272.

WALTHER, L.: Erfahrungen mit Morphindurant bei Dauerschmerzen (Experiences with morphindurant in the treatment of prolonged pain). Medizinische Klinik, Berlin, 1951, 46:33, p. 887.

WEIL, Paul B.; WEISS, U.: Structure of morphine (II). Bulletin on Narcotics, United Nations, 1951, 3:2, pp. 12-31.

WHYTE, H. M.: The effect of aspirin and morphine on heat pain. Clinical Science, 1951, 10:3, pp. 333-345.

WIKLER, A.: Sites and mechanisms of action of morphine and related drugs in the central nervous system. Journal of Pharmacology and Experimental Therapeutics, 1950, 100:4-2, pp. 435-506

. C. OTHER PHENANTHRENE ALKALOIDS AND DERIVATIVES OF OPIUM (UNDER THE CONVENTIONS)

APPELBAUM, E.; KALKSTEIN, M.: Artificial transmission of viral hepatitis among intravenous diacetylmorphine addicts. Journal of the American Medical Association, 1951, 147:3, pp. 222-224.

BAIZER, Manuel M.: Dihydrocodeinone and its bitartrate from codeine. U S. Patent, 1951, 2,544,291.

BAIZER, M. M.; ELLNER, K. S.; LOTER, A.: The rearrangement of codeine to dihydrocodeinone. Journal of the American Pharmaceutical Association, 1951, 40, pp. 580-582.

BAIZER, M. M.; LOTER, A.; ELLNER, K S.; SATRIANA, D. R.: Reactions of alkoxides with certain hydrogenated alkaloids of the morphine series. Journal of Organic Chemistry, 1951, 16, pp. 543-549.

BONNYCASTLE, D. D.; IPSEN, J.; MOLLAND, J.: An examination of the synergism in the actions of codeine and acetylsalicylic acid. Acta Pharmacologica et Toxicologica, 1950, 6:4, pp. 354-363.

CHABRIER, P.; GIUDICELLI, R.; KRISTENSSON, K.: Etude chimique pharmacologique de quelques nouveaux dérivés de la morphine. Comptes rendus de l'Académie des sciences, 1950, 231:4, pp. 289-291.

DENIGÉS, Georges: Caractérisation par microcristalloscopie de l'héroïne et de la dionine. Bulletin des travaux de la Société de pharmacie de Bordeaux, 1950, 88, pp. 165-167.

DEROBERT, L.; LE BRETON, R.: Altération du chlorhydrate d'héroïne en solution aqueuse et application de la règle- mentation des stupéfiants. Annales de médecine légale et de criminologie, 1951, 31, pp. 116-123.

DOUVILLE, J.: L'horo-scope dans la tempête obstétricale en rase campagne. Union médicale du Canada, 1950, 79:12, pp. 1457-1461.

GRECO, S. J. Some pharmaceutical uses of propylene glycol. I. Terpin hydrate and codeine elixir. Journal of the American Pharmaceutical Association, 1951, 12, pp. 536-538.

GROSS, J. B; COMFORT, M. W.; MATHIESON, D. R.; POWER, M. H.: Elevated values for serum amylase and lipase following the administration of opiates: a preliminary report. Proceedings of the Staff Meetings of the Mayo Clinic, 1951, 26:5, pp. 81-87.

HERBERT, F. J.: The use and abuse of codeine. Practitioner, 1951, 167:1001, pp 554-555.

HAGLUND, N. J.; MICHAELSSON, M.: A. method for determining the cough threshold with some preliminary experiments on the effect of codeine. Acta Physiologica Scandinavica, 1950, 21:2-3, pp. 168-173.

HUGGINS, R A.; GLASS, W. G.; BRYAN, A. R.: Protective action of N-allylnormorphine against respiratory depression produced by some compounds related to morphine. Proceedings of the Society for Experimental Biology and Medicine, 1950, 75:2, pp. 540-541.

KARRER, P.; WIDMARK, G Desoxycodein. Helvetica Chimica Acta, 1951, 34:1, pp. 34-38

LANDMANN, H: Das Hustensymptom und seine Behandlung in der Klinik mit Heroin als zeitbedingtem Austauschmittel (Symptomatic cough and its treatment in the clinic with heroin, as a substitute for remedies now unobtainable). Therapie der Gegenwart, 1950, 89.9, pp. 304-307.

LATHAM, M. E; ELLIOTT, H W.: Some aspects of the metabolism of codeine in the rat. Journal of Pharmacology and Experimental Therapeutics, 1951, 101.3, pp. 259-267.

PAVLOVSKAIA, Z. N. Obezbolivanie rodov Tekodinom i Lydolom (Anesthetized childbirth using Tekodin (dihydrohydroxycodeinone hydrochloride) and Lydol). Akusherstvo i Ginekologia, 1949, pp. 6, 8-11.

PEDINELLI, Mario: Sull'alterabilité della codeina con riguardo alla sua determinazione in alcuni prodotti galenici (Instability of codeine in some galenic preparations.) Annali di Chimica Applicata, 1949, 39, pp 512-522.

RADOFF, L. M.; HUGGINS, S E: Protective action of N-allylmorphine against demerol. Proceedings of the Society of Experimental Biology and Medicine, 1951, 78, pp. 879-880.

RAPOPORT, H; BONNER, R. M.: δ7 and δ8 Desoxycodeine. Journal of the American Chemical Society, 1951, 73, pp. 2872-2876.

ROZSA, Pal: The determination of ephedrine hydrochloride and codeine hydrochloride in drug mixtures in the presence of each other. Acta Pharmacologica Hungaricae, 1949, 23, pp. 4-9

SINEL'NIKOVA, B I Vliyanie adrenalina i codeina na kharakter reaktsu Pirke (Effect of adrenaline and codeine on the character of Pirquet's reaction). Voprosy Pediatrii i Okhrany Matcrinstva i Detstva, 1950, 6, pp. 20-21.

SMITH, C C; LEHMAN, E. G; GILLFILLAN, J L.: Antagonistic action of N-allylnormorphine upon the analgetic and toxic effects of morphine, methadone derivatives and isonipecaine Federation Proceedings, 1951, 10:1, pp. 335-336

STORK, G.: The structure of phenoli dihydrothebaine and of β-dihydrothebaine . Journal of the American Chemical Society, 1951, 73, p. 504.

TRENDELENBURG, U.: Ueber die Wirkung emiger Hustenmittel auf Hustenreizschwelle und Atmung (Effect of some sedative cough mixtures on cough-irritation threshold and respiration). Acta Physiologica Scandinavica, 1950, 21:2-3, pp. 174-186.

TSUNENATSU, Fujio; HIROSHI, Sakurai: Determination of atropine in atropine opium-alkaloid injections. Japanese Journal of Pharmacy and Chemistry, 1951, 23, pp. 248-280.

VITOLO, A. E.: Ricerche per la caratterizzazione dell'acetil-dimetil-diidrotebaina (Research for characterization of acetyl-dimethyl-dihydro-thebaine). Bollettino Chimico Farmaceutico, 1951, 90:8, pp. 306-310

WIKLFR, A.: Effects of large doses of N-allylnormorphine on man. Federation Proceedings, 1951, 10:1, p. 345

. D. OTHER DRUGS AND SUBSTANCES DERIVED FROM THE OPIUM POPPYBAIZER, M. M.: Method for producing pure papaverine hydrochloride; U.S Patent 2,507,086 and 2,507,135: and Alkaloid purification; US. Patent 2,507,136.

CENTENERA FONDON, D.: Empleo terapéutico de la papaverina (Therapeutic use of papaverine) Revista Clínica Española, 1950, 39:3, pp. 279-283.

DESRUELLES, M.; FELLION, G A propos des traitements actuels de l'alcoolisme (désintoxication, tetraethylthiuram disulfide, apomorphine). Annales médicopsychologiques, 1951, 109 5, pp. 638-644.

DETRIE, J.; BURKHARD, J. Alcaloides secondaires préparés au cours de la synthèse de la papavérine Produits pharmaceutiques, 1950, 5, pp. 520-521.

FELDBERG, W; PATON, W. D M: Release of histamine from skin and muscle in the cat by opium alkaloids and other histamine liberators. Journal of Physiology, 1951, 114 4, pp. 490-509

HARDMAN, H.; SHERROD, T R.: Comparison of several coronary vasodilators, khelin, papaverine, aminophylline, epinephrine, nor-epinephrine, and neo-synephrine . Federation Proceedings, 1951, 10:1, pp. 305-306.

HENDERSON, F. G.; SHIPLEY, R E; CHEN, K.K.: Pharmacologic studies of 6 7- dimethoxy-1-(4'-theoxy-3'-methoxybenzyl)-3-methyl-iso-quinoline Journal of the American Pharmaceutical Association, 1951, 40:4, pp. 207-210.

HSU, Chih-Yao: Raw materials for pharmaceuticals in Formosa II. Synthetics of the papaverine type Journal of the Taiwan Pharmaceutical Association, 1949, pp. 117-122.

KEWITZ, H.: Untersuchungen uber Papaverin-Karbonsaure (Studies on papaverine carboxylic acid). Archiv fur Experimentelle Pathologie und Pharmakologie (Naunyn-Schmiedeberg's), 1951, 213:1-2, pp. 30-36

LECANNELIER, S.; BARDISA, L.; PFISTER, I: Estudio sobre el mecanismo de acción de la papaverina en el intestino del conejo. Efectos de algunas condiciones metabólicas (Study of the action mechanism of papaverine in the rabbit intestine. Effects of some metabolic conditions). Boletin de la Sociedad Biológica. Concepción, 1950, 25:3-16.

MCCALL, M. L.; FINCH, V.;TAYLOR, H W.: The cerebral effects of papaverine hydrochloride in toxemia of pregnancy. American Journal of Obstetrics and Gynecology, 1951, 61:1, pp. 393-398.

MAYERHOTER, E.: Sechsunddreissig Jahre meiner Papaverintherapie der Spasmen des Pylorus bei Neugeborenen und jungen Sauglingen; alte und neue Indikationen (36 years' experience with the use of papaverine in the treatment of pyloric spasm in the newborn and in younger infants). Annales Paediatrici, 1951, 176:2, pp. 73-81.

MERCIER, F.; MERCIER, J.; COLIN, J.: Influence exercée par la papavérine sur les bronchospasmes histaminiques et acétylcholiniques du cobaye. Comptes rendus des séances de la Société de biologie, 1950, 144:17-18, pp. 1,187-1,190.

MERCIER, F.; MERCIER, J.; SESTIER, M. R: Action spasmolytique expérimentale du papavérinol et de la papavéraldine, alcaloides secondaires préparés au cours de la synthèse de la papavérine Comptes rendus des séances de la Société de biologie, 1951, 145:5-6, pp. 408-410.

MORSIER, G. DE; FELDMANN, H.: Die biologische Behandlung des chronischen Alkoholismus mit Apomorphin (Biological therapy of chronic alcoholism with apomorphine). Deutsche Medizinische Wochenschrift, 1951, 76:1, pp. 22-24.

NAHUNEK, K.: Lecba manicko-melancholické psychosy apomorfinem (Treatment of manic-depressive psychoses with apomorphine). Lekarske Listy, 1950, 5:21, pp. 702-704.

RODIONOV, V. M.; CHENTSOVA, M. G. Vzaimodeictvie kotarnina i gidrastinina i ikh benzoilnykh proizvodnykh s edkimi shchelochami (Reciprocal action of cotarnine and hydrastinine and their benzoyl derivatives with caustic alkalies.) Zhurnal Obshchei Khimii, 1951, 21, pp 321-327.

SACCONI, Luigi: Sui piromeconati di alcuni elementi di transizione (Pyrome conates of some transition elements) Gazetta Chimica Itahana, 1950, 80 pp 372-375.

SAVIOTTI, G: Sintesi industriale della papaverina (Industrial synthesis of papaverine). Farmaco Scienza e Tecmca, 1950, 5 6, pp 721-723

SHEPARD, E. R ; NOTH, J F.: Preparation of some homologs of papaverine Journal American Chemical Society, 1950, 72:10, pp. 4,364-4,368.

TETSUJI KAMETANI: Syntheses of papaverine derivatives. I. Synthesis of 1-(3-methoxy-4-hydroxyphenyl)-3-methyl-

6,7-methylenedroxyisoquinoline. Journal of the Pharmaceutical Society of Japan, 1951, 71, pp. 322-324.

WAHL, Henri La synthèse industrielle de la papavérine et des composés voisins Bulletin de la Société chimique de France, 1951, D1-D8.

WINDER, C. V ; THOMAS, R. W.; KAMM, O . Relative experimental coronary vasodilator potencies of papaverine its ethyl analogue, ethaverine (diquinol, perparin). Journal of Pharmacology and Experimental Therapeutics, 1950, 100 4 1, pp. 482-488.

PART III

A. THE COCA LEAF

CHAMOCHUMBI, M., Nelson: Efectos de la coca sobre el metabolismo de base en sujetos no habituados (Effects of coca on basal metabolism in nonaddicts). Revista de Farmacología y Medicina Experimental, 1949, 2:1, pp. 94-113.

CIUFFARDI, T., Emilio: Contribución a la química del cocaísmo. Revista de Farmacología y Medicina Experimental, 1949, 2:1, pp. 18-93.

CIUFFARDI T., Emilio: Dosis de alcaloides que ingieren los habituados a la coca. Nuevas observaciones (Alkaloid doses ingested by coca-addicts. New observations). Revista de Farmacología y Medicina Experimental, 1948, 1:2, pp. 216-231.

CRUZ SANCHEZ, G.; GUILLEN, A: Estudio químico de las substancias alcalinas auxiliares del cocaísmo Revist de Farmacología y Medicina Experimental, 1948, 1(2), pp. 209-215.

CRUZ SANCHEZ, Guillermo; GUILLEN, Angel: Eliminación de la cocaína en sujetos no habituados (Excretion of cocaine in non-addicts) Revista de Farmacología y Medicina Experimental, 1949, 2:1, p. 17.

GARCÍA GIESMANN, J. M.: Estudio histopatológico del hígado de ratas tratadas con polvos de coca (Histo-pathological study of the liver of rats treated with coca powders). Revista de Farmacología y Medicina Experimental, 1950, 3:1, pp 93-96.

GUTIÉRREZ NORIEGA, Carlos; ZAPATA ORTIZ, V Estudio de habituados a la coca en estado de abstinencia (Study of coca addicts in state of abstinence). Revista de Farmacología y Medicina Experimental, 1950, 3:1, pp. 56-75.

QUIROGA, E : Algunas observaciones sobre sujetos habituados a la coca de Puno. (Observations on coca-addicts of Puno). Revista de Farmacología y Medicina Experimental, 1950, 3:1, pp. 96-98.

ZAPATA ORTIZ, V. Efectos depresivos de la cocaína sobre el sistema nervioso central (Depressive effect of cocaine on the central nervous system). Revista de Farmacología y Medicina Experimental, 1950, 3:1, pp. 1-55.

B. DRUGS MANUFACTURED FROM THE COCA LEAF

D'ANNA, A.; GIUNCHEDI, F.: Azione della cocaina e della adrenalina sul ricambio gassoso delle cavie (Action of cocaine and of adrenaline on gaseous metabolism in guinea pigs). Bolletino della Societé Italiana di Biologia Sperimentale, 1949, 25, pp. 389-390.

BERWICK, M. C.: The effect of anesthetics on calcium release. Journal of Cellular and Comparative Physiology, 1951, 38, pp. 95-107.

DIDIDR, G; CADART, F.; PAULI, A.: A propos de trois observations d'intoxication par la cocaine Journal des sciences médicales de Lille, 1951, 69:11, pp. 294-299.

FOSTER, R. H. K; DAILEY, F. J. Antagonism to cocaine convulsions by 3, 3-diethyl-2, 4-dioxotetrahydropyridine (presidon), pentobarbital, and phenobarbital. Journal of Pharmacology and Experimental Therapeutics, 1950, 9, p. 98.

FURSTENBERG, A. C.; WOOD, L. A; MAGIELSKI, J. E.; MCMAHON, G. F.: An evaluation of cocaine anesthesia: the perpetuation of equivocal concepts. Transactions of the American Academy of Ophthalmology and Otolaryngology, 1951, pp. 643-653.

GUARINO, S.: Action des anesthésiques locaux sur l'effet provoqué par le potassium sur le muscle sartorius de Bufo vulgaris. Comptes rendus de l'Académie des sciences, 1950, 230:21, pp 1907-1908.

GUTIÉRREZ NORIEGA, Carlos Inhibición del sistema nervioso central producida por la intoxicación cocaínica crónica. (Inhibition of the central nervous system induced by chronic cocainism). Revista de Farmacología y Medicina Experimental, 1949, 2:2, pp. 191-235.

GUTIÉRREZ NORIEGA, Carlos: Reflejos de defensa y cocaínismo experimental (Defense reflexes and experimental cocaine addiction). Revista de Farmacología y Medicina Experimental, 1949, 2:2, pp. 236-244.

GUTIÉRREZ NORIEGA, Carlos: Catalepsia producida por intoxicación cocaínica crónica en el Ateleus ater (nota preliminar) (Catalepsy produced by chronic cocaine intoxication in Ateleus ater (preliminary note)). Revista de Farmacología y Medicina Experimental, 1950, 3:1, pp. 85-93.

HEIM, F.; HAAS, A.: Ueber den fermentativen Abbau von Pantokain, Novokain und Kokain durch Extrakte aus Meerschweinchenleber, -niere, -gehirn und -muskulatur (Fermental decomposition of pantocaine, novocaine and cocaine by extracts of the liver, kidneys, brain and musculature of the guinea pig). Archiv für Experimentelle Pathologie und Pharmakologie, 1950, 211:5, pp. 458-461.

INNES, I. R.; KOSTERLITZ, H. W.: The effect of cocaine and chronic sympathetic denervation of the heart on the chronotropic action of adrenaline and noradrenaline British Journal of Pharmacology, 1951, 6, pp 651-658.

LEVY, J.; ZISSMANN, E.: Dosage de faibles quantités de cocaine en présence

d'ecgonine. Journal de physiologie, 1950, 42 3, pp. 499-503.

LORENTE DE NO, R.: Effect of cocaine upon sodium-deficient frog nerve. Journal of General Physiology, 1951, 35, pp. 203-225.

MERCIER, J.: Influence exercée par la cocaine, la pseudococaine droite et la procaine sur la crise audiogene du rat albinos. Journal de physiologie, 1950, 42 :3, pp. 679-683.

SALOMON BUTTLLER, P.: Potenciación del efecto neuro estimulante de la cocaína por substancias alcalinas (Potentiation of the neurostimulatory effect of cocaine by alkaline substances). Revista de Farmacología y Medicina Experimental, 1949, 2:1, pp. 114-137.

SENFF, A. F.: Kurzanalyse mit Kokain (Brief analysis with cocaine). Zeitschrift für Psychotherapie und Medisinische Psychologie, 1951, 1:5, pp 214-217.

STEINHAUS, J. E.; TATUM, A. L: An experimental study of cocaine intoxication and its treatment Journal of Pharmacology and Experimental Therapeutics, 1950, 100.3, pp. 351-361.

WIBAUT, J. P.: Recherches dans le groupe des alcaloides (dérivés de la pyridine, de la piperidine, de la tropinone, de la yohimbine, et de la mimosine [1-leucaenol]. Annales pharmaceutiques françaises, 1951, 9:2, pp. 81-98

WINTER, C. A.; FLATAKER, L.: Effect of antihistaminic drugs upon the performance of trained rats. Journal of

Pharmacology and Experimental Therapeutics, 1951, 101:2, pp. 156-162.

WOODS, L. A.; COCHIN, J; FORNEFELD, E. J.; MCMAHON, F. G.; SEEVERS, M. H.: The estimation of amines in biological materials with critical data for cocaine and mescaline. Journal of Pharmacology and Experimental Therapeutics, 1951, 101.2, pp. 188-199.

WOODS, L. A.; MCMAHON, F. G.; SEEVER, M. H: Distribution and metabolism of cocaine in the dog and rabbit. Journal of Pharmacology and Experimental Therapeutics, 1951, 101:2, pp. 200-204.

YOUNG, Peter A.: The duration of cocaine (and nupercaine) anesthesia in the rabbit cornea. A statistical examination. British Journal of Pharmacology, 1951, 6, pp. 273-285.

PART IV

CANNABIS AND ITS DERIVATIVES

ANONYMOUS: Dagga: South African Medical Journal, 1951, 25:17, pp. 284-286.

BOUQUET, J.: Cannabis. Bulletin on Narcotics, United Nations, 1950, 2:4, pp. 14.-30; 1951, 3:1, pp. 22-45.

DAHI, M. A. Y.: Mechanism of action of synthetic tetrahydrocannabinol (Parahexyl) Federation Proceedings, 1951, 10:1, pp. 290-291.

DUQUENOIS, P.: Chemical and physiological identification of Indian hemp . Bulletin on Narcotics, United Nations, 1950, 2:3, pp. 30-33.

KARBE, H.: Hashish. Arzneimittelforschung, Aulendorf, 1951, 1.1, pp. 37-43

LOEWE, S.: Cannabiswirkstoffe und Pharmakologie der Cannabinole (Active principles of Cannabis and pharmacology of cannabinols). Archiv fur ex- perimentelle Pathologie und Pharmakologie, 1950, 211:2, pp. 175-193.

PULEWKA, P.: Ueber die relative Wirksamkeit türkischer Hanfpflanzen (Relative action of Turkish hemp plants). Archiv für experimentelle Pathologie und Pharmakologie, 1950, 24.23, pp. 278-286.

TAKEDA, Ken-Ichi: Active components of hemp. Kagaku no Ryoiki, 1948, 2, pp. 170-176.

PART V

SYNTHETIC DRUGS
A. GENERAL WORK

*BRUNZELL, Arne: N. F. N. names (Nordic Pharmacopoeia Commission). Svensk Farmaceutisk Tidskrift, 1951, 55, pp. 37-44.

IRWIN, S; HOUDE, R. W.; BENNETT, D. R.; HENDERSHOT, L. C.; SEEVERS, M. H.: The effects of morphine, methadone and meperidine on some reflex responses of spinal animals to nociceptive stimulation Journal of Pharmacology and Experimental Therapeutics, 1951, 101 2, pp. 132-143.

KEWlTZ, H.; REMMER, H. ; ENGELHARDT, H.: Die Wirkung von Morphin, Dolantin und Polamidon auf den Dünndarm des Menschen (Effect of morphine, dolantin and polamidon on the small intestine of man). Klinische Wochenschrift, 1951, 29:31-32, pp. 570-571.

LUDUENA, F. P.; ANANENKO, E.: The pharmacodynamic effects of some new analgesics. Archives Internationales de

Pharmacodynamie et de Thérapeutique, 1950, 81:3, pp. 259-275.

MERCIER, F.; MERCIER, J.; SESTIER, M. R.: Influence exercée par quelques analgésiques centraux synthétiques sur la motricité de la région pylorique chez le chien chloralose. Comptes rendus des séances de la Société de biologie, 1950, 144:21, pp. 1,536-1,538.

PETERSEN, POVL V.: Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone Acta Pharmacologica et Toxicologica, 1951, 7:1, pp. 51-64.

PFEIFFER, C. C.: Synthetic drugs as specific analgesics. Modern Hospital, 1951, 76:3, pp. 100-106.

SCHAUMANN, O.: Die neuen synthetischen Analgetica (New synthetic analgesics.) Scientia Pharmaceutica, 1951, 19, 33-41.

VIDIC, E.: Der Nachweis von Polamidon und Dolantin im Urin and ihre Trennung von Morphin (Determination of polamidon and dolantin in the urine, and their separation from morphine). Archiv für experimentelle Pathologie und Pharmakologie, 1951, 212:5-6, pp. 339-351.

WIBAUT, J. P.: Recherches dans le groupe des alcaloides (dérivés de la pyridine, de la pipéridine, de la tropinone, de la yohimbine et de la mimosine [1-leucaenol] (Alkaloids derived from pyridine, piperidine, tropinone, yohimbine, and mimosine [1-leucaenol]. Annales pharmaceutiques françaises, 1951, 9:2, pp. 81-98.

WILLIAMS, E. M. V.; STREETEN, D. H. P.: The action of morphine, pethidine, and amidon upon the intestinal motility of conscious dogs. British Journal of Pharmacology and Chemotherapy, 1950, 5:4, pp. 461-464.

B. PETHIDINE AND RELATED COMPOUNDS

BARLOW, O ; LEWIS, J R.: Toxicology and addiction liability of meperidine (demerol) in experimental animals. Journal of Pharmacology and Experimental Therapeutics, 1951, 103:1, pp. 147-152.

BLANKE, K.: Ergebnisse der klinischen Erprobung des neuen Analgeticums Cliradon (Results of clinical examination of cliradon, a new analgetic). Medizinische Klinik, 1950, 45:37, pp. 1,171-1,174.

BLAZEBY, R. H.: The position of pethidine in anaesthesia. Anaesthesia, 1951, 6:3, pp. 168-171.

CALESNICK, B.; SMITH, N.H.; BEUTNER, R.: Combined action of cardiotoxic drugs: A study on the acute toxicity of combined quinidine, meperidine, pentobarbital, procaine and procaine amide. Journal of Pharmacology and Experimental Therapeutics, 1951, 102 2 pp. 138-143.

DONATELLI, L.; BUFFONI, F.: Potenziamento della anestesia locale operato dalla mefedina (Augmenting effect of "mefedina" on action of local anesthetics). Archivio Italiano di Scienze Farmacologiche, 1948, 1:2, pp. 87-104.

GAMMELTOFT, A.; JOHANSEN, S. H.; RUBEN, H.: Pethidin ved endoskopi gennem pharynx en ny analgesi-metode for oesofagoskopi og gastroskopi (Pethidine in pharyngeal endoscopy; a new analgesic method in esophagoscopy and gastroscopy). Ugeskrift for Laeger, 1951, 113:17, pp. 525-529.

HAXHOLDT, B. F.: Kvaelstofforilitepethidin anaesthesi med flaxediltil afslappelse (Nitrous oxide-pethidine anesthesia; with flaxedil for relaxation).

Ugeskrift for Laeger, 1951, 113.17, pp. 513-520.

JOHNSON, P. D.: Pethidine as an adjuvant to nitrous oxide and oxygen anaesthesia. British Medical Journal, 1951, 4733, pp. 705-707.

JOHNSTONE, M. Pethidine and general anaesthesia British Medical Journal, 1951, 4737, pp. 943-946.

LINDER, F.; VOLLMAR, J.: Klinische Erfahrungen mit dem synthetischen Analgeticum Cliradon (Ciba 7115) mit vergleichenden Untersuchungen über seine Wirkung auf Atmung, Kreislauf und Warmehaushalt. (Clinical experiences with the synthetic analgetic Cliradone (Ketobemidone, Ciba 7115) with comparative experiments on its effects on respiration, circulation and body temperature). Klinische Wochenschrift, 1950, 28:39-40, pp. 675-681.

LORENZINI, L.: IL cliradon (chloridrato dell'l-metil-4- (m.ossi- fenil) - piperidin-4-etilchetone) nella preparazione alla anestesia (Cliradon (1-methyl-4-(m-hydroxyphenyl)-4-piperidyl ethyl ketone hydrochloride) in preparation for anesthesia). Giornale Italiano di Anestesiologia, 1950, 16:3, pp. 484-490.

MANSON, W. W.: Demerol, scopolamine, and caudal analgesia. United States Armed Forces Medical Journal, 1950, 1:12, pp. 1437-1445.

MARIANA MARELLI, O.: Alterazione delle soluzioni di dolantina per azione del calore (Alterations in dolantin solutions due to the effect of heat). Rendiconti Istituto Superiore di Sanité, 1951, 14:4, pp. 282-286.

McDERMOTT, T. F.; PAPPER, E. M.: Respiratory complications associated with demerol. New York State Journal of Medicine, 1950, 50.14, pp 1721-1726.

MURPHY, M.: Intravenous pethidine. Irish Journal of Medical Science, 1951, 6.311, pp. 535-540.

NEPOLA, S. R.: Clinical experience with demerol comedication in dental local anesthesia. Oral Surgery, Oral Medicine and Oral Pathology, 1951, 4:4, pp. 456-462.

PLOTNIKOFF, N. P.: Distribution of C14 labeled meperidine in the albino rat. Federation Proceedings, 1950, 9:1, p. 308. Journal of Pharmacology and Experimental Therapeutics, 1951, 101, p. 31.

RADOFF, L. M.; HUGGINS, S. E.: Protective action of N-allylmorphine against demerol. Proceedings of the Society of Experimental Biology and Medicine, 1951, 78, pp. 879-880.

ROMANOFF, A.: Demerol habituation in bronchial asthma with report of a case. Annals of Allergy, 1951, 9:1, pp. 95-96.

VARA, P.; KINNUNEN, O.: Cliradonista gynekologin nakokannalta katsottuna (Use of cliradon in gynecology). Duodecim, 1951, 67:1, pp. 3,266-3,329.

VILLA, L.: Ricerche cliniche su un nuovo analgesico di sintesi (Cliradon). (Clinical research on a new synthetic analgesic (Cliradon). Gazzetta Medica Italiana, 1951, 110:7, pp. 222-231.

WINTERS, H. S.; GARCÍA, C. R.; LUBIN, S.: Intravenous demerol in the second stage of labor. American Journal of Obstetrics and Gynecology, 1951, 61:3, pp. 629-634.

ZUCK, D.: A case of pethidine sensitivity. British Medical Journal, 1951, 4698, p. 125.

C. METHADONE AND RELATED COMPOUNDS

ANONYMOUS: Methadone. Army develops perfect substitute for morphine. Delaware State Medical Journal, 1951, 23:1, p. 20.

BEECHER, H. K.; DEFFER, P. A.; FINK, F. E.; SULLIVAN, D. B.: Field use of methadone and levo-iso-methadone in a combat zone (Hamhung-Hungnam, North Korea). United States Armed Forces Medical Journal, 1951, 2:9, pp. 1269-1276.

HERR, F.; PÓRSZÁSZ, H.: Ueber die Wirkung einiger Derivate des Polamidons (2-dimethylamino 4, 4-diphenylheptan-5-ons) (Activity of some derivatives of 6-dimethylamino-4:4 diphenyl-3-heptanone (methadone, polamidone) ). Naunyn-Schmiedeberg Archiv für experimentelle Pathologie, 1950, 210:3, pp. 294-304.

HILL, M.: "Heptalgin" as an obstetric analgesic. Medical Journal of Australia, 1951, 1:5, pp. 212-214.

KRAPCHO, John: Synthetic analgesics. Cyclic analogs of amidone. University Microfilms (Ann Arbor, Michigan), 1951, Pub. No. 2417, 110 p.; Microfilm Abstracts 11, 1951, No. 2, pp. 264-266.

OFNER, P.: Amidone. Some isomeric chlorodialkyl-aminopropanes and their reaction with diphenylmethyl cyanide. Journal of Chemical Society, 1951, pp. 1800-1803.

PAVLOVSKAIA, Z. N.: Obezbolivanie rodov tekodinom i lidolom. (Anesthetized childbirth using Tekodin (dihydrohydroxycodeinone hydrochloride) and Lydol). Akusherstvo i Ginekologiia, 1949, 6, pp. 8-11.

PIECK, K.: Gibt es eine Polamidonsucht? (Addiction to polamidon). Medizinische Klinik, 1950, 45:45, pp. 1429-1432.

SCHADER, H. E.: Zur Verwendung von Polamidon in der Morphinentziehung (Use of polamidon in morphine withdrawal). Medizinische Klinik, 1950, 45:43, pp. 1369-1371.

SCHAEFER, H.: über die Verwendung von Polamidon in der Kieferheilkunde (Use of polamidon in stomatology). Zahnärztliche Welt, 1951, 6:5, pp. 125-126.

SMITH, C. C; LEHMAN, E G.; GILLFILLAN, J. L.: Antagonistic action of N-allyl-normorphine upon the analgetic and toxic effects of morphine, methadone derivatives and isonipecaine. Federation Proceedings, 1951, 10:1, pp. 335-336.

SNYDER, F. F.: Action of levo-iso methadone during labor. Federation Proceedings, 1951, 10:1, pp. 129-130.

SOEHRING, K.; LOHR, H., Jr: Experimentelle Beitrage zum Nachweis von Polamidon (Hoechst 10820) im Harn (Experimental data on the determination of Polamidon (Hoechst 10820) in the urine) Pharmazie, 1950, 5:12, pp. 569-571.

WATTS, D T: The effect of methadone isomers, morphine and pentobarbital on the blood glucose of dogs Journal of Pharmacology and Experimental Therapeutics, 1951, 102:4, pp. 269-271.

WAY, E L; SIGNOROTTI, B. T.; MARCH, C. H; PENG, C. T.: Studies on the urinary, fecal and bihary excretion of d,l methadone by countercurrent distribution

Journal of Pharmacology and Experimental Therapeutics, 1951, 101:3, pp. 249-258.

ZOBOLI, P.: Influenza dell'ete e della nutrizione sull'attvité, dell'amidone (Influence of age and nutrition on activity of amidone). Acta Anesthesiologica (issued with Acta Chirurgica Belgica), 1950, 1:6, pp. 483-489.

D. MORPHINAN AND MORPHINE SYNTHESIS

BELOHLAV, L.: (Syntheses in the morphine series). Oesterreichische Chemiker-Zeitung, 1951, 52, pp. 233-241.

FROMHERZ, K.: Pharmacological effects of 3- hydroxy - N - methyl - morphinan. Archives internationales de pharmacodynamie et de thérapie, 1951, 85, pp. 387-398.

GINSBURG, D.; PAPPO, R.: Preliminary syntheses in the morphine series II Journal of the Chemical Society, 1951, pp. 516-519.

GLASSON, B.: Etat actuel de la question des succédanés synthétiques de la morphine. Revue médicale de la Suisse romande, 1951, 71:7, pp. 484-492.

HOFFMANN, F.; LAROCHE ET Co. A. G. (3-hydroxy-N-methylmorphinan and its salts). German Patent 802.571, 1951.

KEUTMANN, E.; FOLDES, F. F: The analgesic effect of dromoran hydrobromide (3-hydroxy-N-methylmorphinan hydrobromide) in post-operative pain New England Journal of Medicine, 1951, 244:8, pp. 286-288.

LEE, R. E.; PFEIFFER, C. C: Influence of analgesics. Dromoran Nisentil and morphine on pain thresholds in man. Journal of Applied Physiology, 1951, 4:3, pp. 193-198.

SUTER, C. M.: Medicinal Chemistry, John Wiley and Sons, Inc.: New York, 1951, vol. I, vi, 473 pp., (Analgesics: A Aralkylamines by Fellows, E J; Ullyot, G. E.; B. Partial structures related to morphine by Lee, J.).

E. OTHER SYNTHETIC ANALGESICS

ADAMSON, D. W.; DUFFIN, W. M; GREEN, A. F.: Dithienylbutylamines as analgesics. Nature, 1951, 167:4239, pp. 153-154.

CORDIER, G. J.; LESPAGNOL, A.; MERCIER, F.: Pouvoir analgésique d'un dérivé de la diphényl-ethylamine. Presse médicale, 1950, 58:83, pp 1502-1503.

KYI Z. Y.; WILSON, W.: Synthetic analgesics and related compounds II. Some derivatives of 3,7-diazabicyclo (3.3.1) nonane (bispidine). Journal of the Chemical Society, 1951, pp 1706-1708.

LA BARRE, J.; HANS, M. J.: A propos des propriétés antipyrétiques et analgésiques de la formyl-4-antipirine. Archives internationales de pharmacodynamie et de thérapie, 1951, 86:2, pp. 227-235.

LAYANI, F; ROESER, J.: Un nouvel analgésique à action prolongée: le dérivé di-iodé de l'alcool hydroxybenzylique. Revue du rhumatisme, 1950, 17:12, pp. 641-643.

LEWIS, J R.: Pharmacology of N-(2-(2-pyridyl) ethyl) phthalimide hydrochloride, a new analgesic. Archives internationales de pharmacodynamie et de thérapie, 1951, 88, pp. 142-158.

MERCIER, F.; MERCIER, J.; -MARINACCE, P.; TARDIEU, J.: Sur l'action analgésique expérimentale de deux dérivés de la diphenylethylamine. Comptes rendus de la Société française de biologie, 1950, 144, pp 1193-1195.

PAPA, D.; SCHWENK, E; VILLANI, F.; KUNGSBERG, E.: The analgesic activity of N.N-dialkylamides. Journal of the American Chemical Society, 1950, 72:9, pp. 3885-3886.

WILSON III, J. W.; ZIRKLE, C L.; ANDERSON, E. L.; STEHLE, J. J.; ULLYOT, G. E.: Analgesics III. Aminophthalidylakanes. Journal of Organic Chemistry, 1951, 16, pp 792-799.

PART VI

ADDICTION TO NARCOTIC DRUGS

ANONYMOUS: Narcotics Anonymous. American Journal of Public Health, 1951, 41, p. 254.

ATKINS, K. K.: A narcotic control system for use in the small hospital. Hospitals, 1951, 25:2, pp. 95-98

BARLOW, O. W.; LEWIS, J. R.: Toxicology and addiction liability of meperidine (demerol) in experimental animals. Journal of Pharmacology and Experimental Therapeutics, 1951, 103:2, pp. 147-152.

BECKER, A. M.: Zur Suchtfrage bei neuen Analgetics (6-Dimethylamino-4, 4-diphenyl-3-Heptanon, "Heptadon") (Addiction to new analgesics (6-Di-methylamino-4, 4-diphenyl-3-Heptanon, "Heptadon")). Wiener Medisinische Wochenschrift, 1950, 100:49-50, pp 50-53.

BELLING, G.: Narkotiske forgiftninger behandlet pa Bornholms Amtssygehus, medicinsk afdeling, fra 1936-1950 (Cases of narcotic poisoning at Bornholm County Hospital 1936-1950). Ugeskrift for Laeger, 1950, 112:51, pp. 1747-1749.

BERRY, L. H.: Medical counseling clinics for young narcotic addicts. Journal of the American Dental Association, 1951, 147:12, pp. 1129-1132.

BOSWELL, W. H.: Narcotic addiction. Management of withdrawal symptoms with cortisone. United States Armed Forces Medical Journal, 1951, 2.9, 1347-1351.

CHILD, G. P.: The treatment of opiate addiction with intravenous alcohol. New York State Journal of Medicine, 1951, 51.12, pp. 1521-1523.

CONNERY, G. E.: Control of narcotic addiction. Journal of the American Dental Association, 1951, 147:12, pp. 1162-1165.

COREY, Stephen J. (Rev.) A chaplain looks at drug addiction. Federal Probation, 1951, 15:3, pp. 17-24.

DR MATTEI, P.: Modificazioni degli analizzatori corticali e perifici nell'eb-

BULLETIN ON NARCOTICS l JULY-SEPTEMBER 1952 51 brezza da stupefacenti (Modifications of cortical and peripheral analysors in narcotic intoxication ). Giornale di Medicina Militare, 1951, 101 (Spec. No), pp. 144-147.

FARAGO, I.: K?b?t?szerbetegs?gek keletkez?serol, es megjelen?si form?irol (On the origin and manifestations of narcotic diseases) Magyar Belorvosi Archivum, 1951, 4:2, pp. 88-93

FECHNER, J.: Sodium amytal addiction with an acute toxic psychosis. Delaware State Medical Journal, 1951, 23 8, pp. 231-232.

HAZARD, R.: Accoutumance aux stupéfiants, étude générale. Thérapie, 1950, 5:6, pp. 276-277.

HEUYER, G.; MICHAUX, L.: Traitement de l'accoutumance et du sevrage. Thérapie, 1950, 5:6, pp. 279-280.

ISBELL, H.: What to know about drug addiction. General Practitioner, 1951, 4:3, pp. 45-52.

ISBELL, H.: Meeting a growing menace: drug addiction. Merck Report, 1951, 60:3, pp. 4-9.

JOHNSTON, M.: An experiment in group psychotherapy with the narcotic addict. American Journal of Physiology, 1950, 163:3, pp. 24-31.

KNIGHT, R. G.; PROUT, C. T.: A study of results in hospital treatment of drug addictions. American Journal of Psychiatry, 1951, 108 3, pp. 303-308.

MUHLAU, M.: Zur Frage der Polamidonsucht, vom gerichtsmedizinischen Standpunkt (Forensic aspects of polamidon addiction). Aerstliche Wochenschrift, 1951, 6:33, pp 779-787.

SATTFS, H: Zur Polamidonsucht (Polamidon addiction). Deutsche medizinische Wochenschrift, 1951, 70.29-30, pp. 929-931.

SEVKI D?R?SKEN, O.: (Detection of morphine alkaloids in cerebrospinal fluid of heroine addicts) Istanbul Seririyati, 1950, 32, pp. 20-21.

TU, Prof. Tsungming: Statistical studies on the mortality rates and the causes of death among the opium addicts in Formosa, Bulletin on Narcotics, United Nations, 1951, 3:2, pp. 9-11.

VAILLE, C ; STERN, G. Contribution à l'étude des toxicomanies. III.-Quelques-uns de leurs aspects médicosociaux Annales pharmaceutiques françaises, 1950, 8:1, pp. 111-120.

VAISBERG, M.: Benadryl - its uses in the narcotic withdrawal syndrome and in other conditions. Annals of Allergy, 1950, 8:4, pp. 74-76.

VERTH, C.: Pervitinbehandlung bei Schlafmittelvergiftung (Pervitin therapy in poisoning with narcotics). Deutsche Gesundheitswesen, 1951, 76:23, pp. 806-807.

VOGEL, VICTOR H ; ISBELL, H. Medical aspects of addiction to analgesic drugs Bulletin on Narcotics, United Nations, 1950, 2.4, pp 31-40.

WIKLER, A.: Clinical aspects of diagnosis and treatment of addictions. Bulletin of the Menninger Clinic, 1951, 15:5, pp. 157-166.

WILLIAMS, E. Y: Treatment of drug addiction; preliminary report Psychiatric Quarterly, 1951, 25:4, pp. 604-612.

WILZBACH, C. A. Preventing narcotic addiction. Cincinnati Journal of Medicine, 1951, 32.10, pp. 426-427.

WOLFF, P.O.: Quelques aspects actuels de la toxicomanie. Thérapie, 1950, 5.6, pp. 278-279.

WOLFF, P. O: Some aspects of drug addiction. Journal of Pharmacy and Pharmacology, 1951, 3:1, pp. 1-16.

ZIMMERING, P.; TOOLAN, J.; SAFRIN, R.; WORTIS, S. B.: Heroin addiction in adolescent, boys Journal of Nervous and Mental Disease, 1951, 114:1, pp. 19-34.

PART VII

MISCELLANEOUS

FOCACCIA, S.: Studio medico e farmacologico su una pianta tropicale: il ciat (Medical and pharmacologic studies on a tropical plant: Celastrus). Annali di Medicina Navale e Coloniale, 1950, 55:6, pp. 783-787.

CHATTERJEE, A. (n?e MOOKHERJEE): The alkaloid of Rauwolfia canescens.

Journal of the Indian Chemical Society, 1951, 28, pp. 29-33.

CHATTERJEE, A.; BOSE, S.: A new alkaloid from the root of Rauwolfia serpentina Benth. Science and Culture, 1951, 17:3, p. 139.

GUPTA, J. C.; ROY, P. K.; RAY, G. K.; GANGULY, S.C. A preliminary note on the excretion of Rauwolfia total alkaloids in urine (Indigenous drugs inquiry, IRFA, Calcutta). Indian Journal of Medical Research, 1950, 38:1, pp. 67-73.